Kifgslafl

Kifgslafl

SCHEMBL29356758

CC[C@H](C)[C@H](NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.57
OPRM1 P35372 4/20 0.55
OPRD1 P41143 4/20 0.55
OPRK1 P41145 2/20 0.54
NTSR2 O95665 1/20 0.53
NTSR1 P30989 1/20 0.53
NPBWR1 P48145 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31256987 0.93 OPRD1 (0.61) OPRM1OPRD1OPRK1NPBWR1
SCHEMBL30527908 0.90 BACE1 (0.59) BACE1
SCHEMBL38652693 0.89 BACE1 (0.59) BACE1
SCHEMBL38652561 0.89 BACE1 (0.59) BACE1
SCHEMBL29966011 0.89 BACE1 (0.59) BACE1OPRM1OPRD1OPRK1
SCHEMBL29416071 0.88 BACE1 (0.58) BACE1
SCHEMBL31257045 0.88 OPRM1 (0.56) BACE1OPRM1OPRD1OPRK1
SCHEMBL30168332 0.87 BACE1 (0.58) BACE1OPRM1OPRD1OPRK1NPBWR1
SCHEMBL30900783 0.86 TFPI (0.58) OPRM1OPRD1OPRK1NPBWR1
SCHEMBL29494697 0.86 NTSR2 (0.63) BACE1OPRK1NTSR2NTSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 844 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094973-A T cell receptor 2026-05-26 CN claimed
US-20260137817-A1 COMBINATION CANCER IMMUNOTHERAPY WITH PENTAAZA MACROCYCLIC RING COMPLEX GALERA LABS LLC (US) 2026-05-21 US claimed
EP-4735471-A2 T-CELL RECEPTORS Ospedale San Raffaele S.r.l. (IT) 2026-05-06 EP claimed
US-20260069697-A1 METHOD OF TREATING CANCER INTENSITY THERAPEUTICS INC (US) 2026-03-12 US claimed
CN-120082510-A Immune cell culture medium and immune cell culture method 广东德力泰生物医药科技有限公司 2025-06-03 CN claimed
WO-2025003481-A2 T-CELL RECEPTORS OSPEDALE SAN RAFFAELE S.R.L. (IT) 2025-01-02 WO claimed
CN-119120412-A Vaccine based on protein CAMKII binding domain, preparation method and application 南京邮电大学 2024-12-13 CN claimed
CN-118987015-A Application of antisense oligonucleotide in preparation of medicine for treating breast cancer 北京悦康科创医药科技股份有限公司 2024-11-22 CN claimed
CN-118731249-A Simultaneous separation and determination method for terminal modified decafluorobiphenyl polypeptide drug and related substances thereof 无锡学院 2024-10-01 CN claimed
US-20240299544-A1 CANCER THERAPIES COMPRISING PEPTIDE LOADED CXCR3- AND CCR5-INDUCING DENDRITIC CELLS AND CHEMOKINE MODULATORY AGENTS H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. 2024-09-12 US claimed
US-20240148714-A1 Triple Negative Breast Cancer Treatment Method EXELIXIS, INC. 2024-05-09 US claimed
EP-4355359-A1 CANCER THERAPIES COMPRISING PEPTIDE LOADED CXCR3- AND CCR5-INDUCING DENDRITIC CELLS AND CHEMOKINE MODULATORY AGENTS Health Research, Inc. (US) 2024-04-24 EP claimed
US-20230338251-A1 METHOD OF TREATING CANCER INTENSITY THERAPEUTICS, INC. 2023-10-26 US claimed
US-20230190933-A1 Immunologically Active Peptide-Biliverdin Conjugate, Preparation Method Therefor and Application Thereof INSTITUTE OF PROCESS ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) 2023-06-22 US claimed
US-11564987-B2 Combination immunotherapy for treatment of triple-negative breast cancer SLSG LIMITED LLC (US) 2023-01-31 US claimed
WO-2022266390-A1 CANCER THERAPIES COMPRISING PEPTIDE LOADED CXCR3- AND CCR5-INDUCING DENDRITIC CELLS AND CHEMOKINE MODULATORY AGENTS HEALTH RESEARCH, INC. (US) 2022-12-22 WO claimed
US-20220118119-A1 COMBINATION CANCER IMMUNOTHERAPY WITH PENTAAZA MACROCYCLIC RING COMPLEX BIOSSIL INC. (CA) 2022-04-21 US claimed
US-20260146040-A1 USE OF CASEINOLYTIC PROTEASE P FUNCTION AS A BIOMARKER OF DRUG RESPONSE TO IMIPRIDONE-LIKE AGENTS Madera Therapeutics, LLC (US) 2026-05-28 US disclosed
WO-2022020364-A1 PREVOTELLA HISTICOLA STRAIN C AS AN ORAL THERAPY FOR INFLAMMATORY DISEASES EVELO BIOSCIENCES, INC. (US) 2022-01-27 WO disclosed
US-20220025034-A1 METHODS OF TREATING IMMUNOTHERAPY-RELATED TOXICITY USING A GM-CSF ANTAGONIST HUMANIGEN, INC. (US) 2022-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146040-A1 USE OF CASEINOLYTIC PROTEASE P FUNCTION AS A BIOMARKER OF DRUG RESPONSE TO IMIPRIDONE-LIKE AGENTS CTRB1, CTRB2, CPN1 BACE1 880/4885OPRM1 1377/4885OPRD1 576/4885
US-20230190933-A1 Immunologically Active Peptide-Biliverdin Conjugate, Preparation Method Therefor and Application Thereof VIP, CD74, WASF2 BACE1 2003/4885OPRM1 4112/4885OPRD1 3979/4885
US-20260137817-A1 COMBINATION CANCER IMMUNOTHERAPY WITH PENTAAZA MACROCYCLIC RING COMPLEX CD274, PDCD1, PDCD1LG2 BACE1 3138/4885OPRM1 357/4885OPRD1 1096/4885
US-20240148714-A1 Triple Negative Breast Cancer Treatment Method BRCA1, ABL1, STAT5B BACE1 4511/4885OPRM1 3572/4885OPRD1 3308/4885
US-20230338251-A1 METHOD OF TREATING CANCER PBK, GZMB, NPC1L1 BACE1 2422/4885OPRM1 2532/4885OPRD1 3151/4885
US-20220118119-A1 COMBINATION CANCER IMMUNOTHERAPY WITH PENTAAZA MACROCYCLIC RING COMPLEX CD274, PDCD1, PDCD1LG2 BACE1 2880/4885OPRM1 4381/4885OPRD1 4725/4885
US-20260069697-A1 METHOD OF TREATING CANCER PBK, GZMB, KLRK1 BACE1 1688/4885OPRM1 2071/4885OPRD1 1578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.