SCHEMBL29357289

SCHEMBL29357289

CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCSC)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C(C)C)C(C)C

nearest known ligand 0.88

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTH1R Q03431 15/20 0.88
GLP1R P43220 2/20 0.75
CCKBR P32239 1/20 0.75
NR3C1 P04150 2/20 0.69
GRPR P30550 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Teriparatide SCHEMBL720581 0.94 PTH1R (0.90) PTH1RGLP1RCCKBR
Teriparatide SCHEMBL29354459 0.94 PTH1R (0.91) PTH1RGLP1RCCKBR
SCHEMBL28980015 0.94 PTH1R (0.91) PTH1RGLP1RCCKBR
SCHEMBL1773403 0.92 PTH1R (0.85) PTH1RGLP1RCCKBR
SCHEMBL29354319 0.90 GLP1R (0.81) PTH1RGLP1RCCKBRNR3C1
SCHEMBL15268863 0.90 GLP1R (0.81) PTH1RGLP1RCCKBRNR3C1
Teriparatide SCHEMBL29357752 0.90 PTH1R (0.85) PTH1RGLP1RCCKBR
Hydrochloric Acid SCHEMBL29363528 0.90 GLP1R (0.80) PTH1RGLP1RCCKBRNR3C1
SCHEMBL29376455 0.90 PTH1R (0.81) PTH1RGLP1RCCKBRNR3C1
Teduglutide SCHEMBL20898050 0.89 GLP1R (0.82) PTH1RGLP1RCCKBRNR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118126197-A Recombinant PTH fusion protein and construction method and application thereof 康众(广东)生物医药有限公司 2024-06-04 CN claimed
US-12534511-B2 Serum albumin-binding fibronectin type III domains BRISTOL-MYERS SQUIBB COMPANY (US) 2026-01-27 US disclosed
US-12529088-B2 Helper factors for expressing proteins in yeast LONZA LTD (CH) 2026-01-20 US disclosed
EP-3833622-B1 TRANSFER STATION FOR API SEED CRYSTALS LONZA AG (CH) 2025-12-24 EP disclosed
US-12497624-B2 Methods for improving production of biological products by reducing the level of endogenous protein LONZA LTD (CH) 2025-12-16 US disclosed
EP-4638756-A1 HOST CELLS WITH PAT1 KNOCKOUT FOR INCREASED SPECIFIC PROTEIN PRODUCTIVITY Lonza Ltd. (CH) 2025-10-29 EP disclosed
EP-4608986-A1 IMPROVED METHOD TO INCREASE DRUG SUBSTANCE YIELD PharmaEssentia Corporation (TW) 2025-09-03 EP disclosed
US-12404309-B2 Host cell for producing a protein of interest LONZA LTD (CH) 2025-09-02 US disclosed
US-12371650-B2 Method and system for providing buffer solutions LONZA LTD (CH) 2025-07-29 US disclosed
US-12352625-B2 Automated control of cell culture using Raman spectroscopy LONZA LTD (CH) 2025-07-08 US disclosed
EP-3572424-B1 SERUM ALBUMIN-BINDING FIBRONECTIN TYPE III DOMAINS BRISTOL MYERS SQUIBB CO (US) 2022-04-20 EP disclosed
WO-2022069613-A1 HOST CELLS OVEREXPRESSING TRANSLATIONAL FACTORS LONZA LTD (CH) 2022-04-07 WO disclosed
US-20220106800-A1 CUSTOMIZABLE FACILITY LONZA LTD (CH) 2022-04-07 US disclosed
EP-3874047-B1 CARBON-SOURCE REGULATED PROTEIN PRODUCTION IN A RECOMBINANT HOST CELL LONZA AG (CH) 2022-04-06 EP disclosed
US-11279922-B2 Delivery of therapeutic agents by a collagen binding protein THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2022-03-22 US disclosed
US-20220049275-A1 SSI CELLS WITH PREDICTABLE AND STABLE TRANSGENE EXPRESSION AND METHODS OF FORMATION LONZA AG (CH) 2022-02-17 US disclosed
US-20220042064-A1 CARBON-SOURCE REGULATED PROTEIN PRODUCTION IN A RECOMBINANT HOST CELL LONZA LTD (CH) 2022-02-10 US disclosed
EP-3947695-A1 MUT- METHYLOTROPHIC YEAST Universität für Bodenkultur Wien (AT) 2022-02-09 EP disclosed
US-11236520-B2 Customizable facility LONZA LTD (CH) 2022-02-01 US disclosed
EP-3942014-A1 CONTINUOUS BLADE IMPELLER Lonza Ltd. (CH) 2022-01-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534511-B2 Serum albumin-binding fibronectin type III domains FN1, ALB, FGB PTH1R 3344/4885GLP1R 4287/4885CCKBR 4851/4885
US-11279922-B2 Delivery of therapeutic agents by a collagen binding protein PTH1R, GHRHR, FGF23 PTH1R 1/4885GLP1R 134/4885CCKBR 148/4885
US-12529088-B2 Helper factors for expressing proteins in yeast UPF1, ILF3, YIF1A PTH1R 2916/4885GLP1R 4828/4885CCKBR 4880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.