E324

E324

SCHEMBL29357397

CCOc1ccc2c(c1)C(C)=CC(C)(C)N2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 12/20 1.00
KDM4E B2RXH2 8/20 1.00
HPGD P15428 8/20 1.00
HSD17B10 Q99714 7/20 1.00
LMNA P02545 7/20 1.00
MEN1 O00255 6/20 1.00
KMT2A Q03164 6/20 1.00
TDP1 Q9NUW8 5/20 1.00
CYP3A4 P08684 3/20 1.00
ALOX12 P18054 2/20 1.00
CYP1A2 P05177 2/20 1.00
CYP2D6 P10635 2/20 1.00
CYP2C9 P11712 2/20 1.00
CYP2C19 P33261 2/20 1.00
ALOX15 P16050 1/20 1.00
HIF1A Q16665 1/20 1.00
GAA P10253 2/20 0.61
MAPT P10636 11/20 0.59
L3MBTL1 Q9Y468 4/20 0.59
MAPK1 P28482 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
E324 SCHEMBL21601 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDHSD17B10LMNA
E324 SCHEMBL7999894 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDHSD17B10LMNA
E324 SCHEMBL27554157 0.98 ALDH1A1 (0.97) ALDH1A1KDM4EHPGDHSD17B10LMNA
E324 SCHEMBL27314758 0.98 ALDH1A1 (0.97) ALDH1A1KDM4EHPGDHSD17B10LMNA
E324 SCHEMBL27371041 0.98 ALDH1A1 (0.97) ALDH1A1KDM4EHPGDHSD17B10LMNA
E324 SCHEMBL27419374 0.98 ALDH1A1 (0.97) ALDH1A1KDM4EHPGDHSD17B10LMNA
E324 SCHEMBL11191719 0.98 ALDH1A1 (0.97) ALDH1A1KDM4EHPGDHSD17B10LMNA
E324 SCHEMBL8118295 0.98 ALDH1A1 (0.97) ALDH1A1KDM4EHPGDHSD17B10LMNA
E324 SCHEMBL27325190 0.98 ALDH1A1 (0.97) ALDH1A1KDM4EHPGDHSD17B10LMNA
E324 SCHEMBL27951085 0.98 ALDH1A1 (0.97) ALDH1A1KDM4EHPGDHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022229983-A1 SUGAR ESTERS AND SUGAR ALCOHOL ESTERS OF SHORT CHAIN FATTY ACIDS AND COMPOSITIONS THEREOF FERTIS INDIA PVT. LTD. (IN) 2022-11-03 WO claimed
US-12589075-B2 Osmotic dosage forms comprising deutetrabenazine and methods of use thereof AUSPEX PHARMACEUTICALS LLC (US) 2026-03-31 US disclosed
US-12447182-B2 Swine origin probiotics that promote health and growth performance in pigs THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2025-10-21 US disclosed
US-20250313777-A1 TREATMENT COMPOSITIONS COMPRISING ETHOXYQUIN PROCTER & GAMBLE COMPANY, THE 2025-10-09 US disclosed
WO-2025199382-A1 TREATMENT COMPOSITIONS COMPRISING ETHOXYQUIN THE PROCTER & GAMBLE COMPANY (US) 2025-09-25 WO disclosed
US-12364720-B2 Bacillus strains improving health and performance of production animals NOVOZYMES A/S (DK) 2025-07-22 US disclosed
US-12325646-B2 Fertigation water treatment UNIVERSITY OF GUELPH (CA) 2025-06-10 US disclosed
US-20250121016-A1 SWINE ORIGIN PROBIOTICS THAT PROMOTE HEALTH AND GROWTH PERFORMANCE IN PIGS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS 2025-04-17 US disclosed
US-12220435-B2 Swine origin probiotics that promote health and growth performance in pigs THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2025-02-11 US disclosed
US-20240307313-A1 OSMOTIC DOSAGE FORMS COMPRISING DEUTETRABENAZINE AND METHODS OF USE THEREOF AUSPEX PHARMACEUTICALS LLC 2024-09-19 US disclosed
CN-114501995-A Agricultural and horticultural insecticide or animal external or internal parasite control agent containing substituted cyclopropane oxadiazolyl-containing imidazopyridazine compound or salt thereof as active ingredient, and method for using same 日本农药株式会社 2022-05-13 CN disclosed
US-20220143110-A1 Bacillus Strains Improving Health and Performance of Production Animals NOVOZYMES A/S (DK) 2022-05-12 US disclosed
EP-3990605-A1 CLEANING COMPOSITION The Procter & Gamble Company (US) 2022-05-04 EP disclosed
CN-110121500-B 4H-pyrrolopyridine compound or salt thereof, agricultural or horticultural insecticide containing same, and method for using same 日本农药株式会社 2022-05-03 CN disclosed
CN-110114354-B Condensed heterocyclic compound having oxime group or salt thereof, agricultural and horticultural insecticide containing the same, and method of using the same 日本农药株式会社 2022-04-29 CN disclosed
CN-114401967-A Agricultural and horticultural insecticide or external or internal parasite control agent for animals containing imidazopyridazine compound or salt thereof as active ingredient, and method of use thereof 日本农药株式会社 2022-04-26 CN disclosed
CN-114223661-A Use of acyclic picolinamides as fungicides for controlling phytopathogenic fungi in row crops 美国陶氏益农公司 2022-03-25 CN disclosed
CN-114144419-A Oxazepinotrienone derivative, agricultural or horticultural insecticide containing the derivative, and method of using the same 日本农药株式会社 2022-03-04 CN disclosed
US-20220023283-A1 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF DEMENTIA AND CEREBROVASCULAR DISORDERS FUSO PHARMACEUTICAL INDUSTRIES, LTD. (JP) 2022-01-27 US disclosed
EP-3942010-A1 PROCESS OF LAUNDERING FABRICS The Procter & Gamble Company (US) 2022-01-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220023283-A1 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF DEMENTIA AND CEREBROVASCULAR DISORDERS HTR3B, HTR3A, HTR2A ALDH1A1 2184/4885KDM4E 1814/4885HPGD 1115/4885
US-12589075-B2 Osmotic dosage forms comprising deutetrabenazine and methods of use thereof SLC6A3, HTT, PARK7 ALDH1A1 3515/4885KDM4E 1600/4885HPGD 1797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.