Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 5/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4802675 | 0.87 | GAA (0.46) | MEN1KMT2ACA2GAAMAPT | |
| SCHEMBL1233033 | 0.86 | IDO1 (0.34) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL1144737 | 0.84 | MAPT (0.42) | KMT2AMAPTSMN1; SMN2NPC1MAPK1 | |
| SCHEMBL8431458 | 0.81 | GAA (0.35) | GAAGABRA1GABRB2 | |
| SCHEMBL1274016 | 0.81 | KDM4E (0.41) | MEN1KMT2AKDM4EESR1GAA | |
| SCHEMBL7759240 | 0.80 | CYP3A4 (0.36) | KDM4EESR1ESR2GAASMN1; SMN2 | |
| SCHEMBL6402971 | 0.76 | CA2 (0.38) | CA2ALDH1A1GRM2GABRA1GABRB2 | |
| SCHEMBL5603503 | 0.73 | CA2 (0.34) | CA2GABRA1GABRB2 | |
| SCHEMBL7576873 | 0.72 | DGKA (0.38) | ESR1ESR2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL29880960 | 0.71 | GAA (0.50) | MEN1KMT2AKDM4EESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229370-A1 | CRYSTALLINE FORM OF 2-(4,6-BIS-BIPHENYL-4-YL-1,3,5-TRIAZIN-2-YL)-5-(2-ETHYL-(N)-HEXYLOXY)PHENOL | BASF SE (DE) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009071475-A1 | CRYSTALLINE FORM OF 2-(4,6-BIS-BIPHENYL-4-YL-1,3,5-TRIAZIN-2-YL)-5-(2-ETHYL-(N)-HEXYLOXY)PHENOL | BASF SE (CH) | 2009-06-11 | — | — | WO | disclosed |
| EP-1824921-A1 | LACTONE STABILIZING COMPOSITIONS | Milliken&Company (US) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006065829-A1 | LACTONE STABILIZING COMPOSITIONS | MILLIKEN & COMPANY (US) | 2006-06-22 | — | — | WO | disclosed |