Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5603503 | 0.80 | CA2 (0.34) | CA2GABRA1GABRB2 | |
| SCHEMBL4802675 | 0.76 | GAA (0.46) | CA2ALDH1A1TSHRTDP1GRM2 | |
| SCHEMBL2935832 | 0.76 | MEN1 (0.37) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| SCHEMBL1233033 | 0.73 | IDO1 (0.34) | ALDH1A1MAOBGRM2NPSR1 | |
| SCHEMBL8431458 | 0.71 | GAA (0.35) | GABRA1GABRB2NPSR1 | |
| SCHEMBL1144737 | 0.71 | MAPT (0.42) | ALDH1A1TSHRMAOAMAOB | |
| SCHEMBL1274016 | 0.68 | KDM4E (0.41) | ALDH1A1TSHRTDP1MAOAMAOB | |
| SCHEMBL3353198 | 0.66 | NR3C1 (0.41) | CA2MAOAMAOBGRM2NPSR1 | |
| SCHEMBL5544519 | 0.65 | MAOA (0.68) | TSHRMAOAMAOBNPSR1 | |
| SCHEMBL4343407 | 0.65 | GABBR2 (0.47) | CA2GABRA1GABRB2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050118248-A1 | Amphiphilic derivatives for the production of vesicles, micelles and complexants, and precursors thereof | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DE (IL) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050118248-A1 | Amphiphilic derivatives for the production of vesicles, micelles and complexants, and precursors thereof | CHMP4B, LIPA, VPS4B | CA2 1939/4885GABRA1 1436/4885GABRB2 2319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.