Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | HRH1 | P35367 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30816200 | 0.79 | PARP1 (0.35) | HTR2AHTR2C | |
| SCHEMBL30817704 | 0.75 | PDE7A (0.41) | — | |
| SCHEMBL30666494 | 0.75 | HSD11B1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL11674689 | 0.71 | HTR2A (0.37) | HTR2AHRH1HTR2BHTR2CAKR1C3 | |
| SCHEMBL6760864 | 0.69 | RORC (0.40) | HTR2AHRH1HTR2BHTR2C | |
| SCHEMBL6760866 | 0.69 | RORC (0.40) | HTR2AHRH1HTR2BHTR2C | |
| SCHEMBL6981687 | 0.66 | THRB (0.35) | AKR1C1KIF11 | |
| Toluene SCHEMBL28973336 | 0.65 | RAB9A (0.53) | NPC1RAB9AAKR1C3AKR1C1ALDH1A1 | |
| Toluene SCHEMBL28973335 | 0.65 | RAB9A (0.53) | NPC1RAB9AAKR1C3AKR1C1ALDH1A1 | |
| SCHEMBL30666720 | 0.65 | SIGMAR1 (0.50) | HTR2AHRH1HTR2BHTR2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941905-A1 | SUMO INHIBITOR COMPOUNDS AND USES THEREOF | Suvalent Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | claimed |