Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 1/20 | 0.49 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | NCF1 | P14598 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5022702 | 1.00 | HTR2A (0.61) | HTR2AHTR2CSLC6A4HTR7KDM4E | |
| SCHEMBL30443783 | 0.83 | KEAP1 (0.52) | HTR2AHTR2CSLC6A4KDM4EALDH1A1 | |
| SCHEMBL31563732 | 0.83 | KEAP1 (0.47) | HTR2AHTR2CSLC6A4KDM4EALDH1A1 | |
| SCHEMBL29118465 | 0.83 | KEAP1 (0.52) | HTR2AHTR2CSLC6A4KDM4EALDH1A1 | |
| SCHEMBL5067333 | 0.81 | KEAP1 (0.55) | KDM4EALDH1A1NCF1 | |
| SCHEMBL10495676 | 0.80 | HTR2C (0.68) | HTR2AHTR2CSLC6A4HTR7KDM4E | |
| SCHEMBL17506189 | 0.80 | NOS3 (0.39) | HTR2AHTR2CSLC6A4HTR7 | |
| SCHEMBL18284881 | 0.79 | ADRA2C (0.58) | KDM4EPRKCQNCF1 | |
| SCHEMBL823332 | 0.79 | ALDH1A1 (0.48) | KDM4EALDH1A1NCF1 | |
| SCHEMBL21384494 | 0.79 | HTR2A (0.61) | HTR2AHTR2CSLC6A4HTR7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12365670-B2 | GLP-IR agonists and uses thereof | QILU REGOR THERAPEUTICS INC. (CN) | 2025-07-22 | — | — | US | disclosed |
| US-20220024901-A1 | GLP-1R AGONISTS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2022-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12365670-B2 | GLP-IR agonists and uses thereof | GLP1R, GPR119, GIPR | HTR2A 638/4885HTR2C 815/4885SLC6A4 2962/4885 |
| US-20220024901-A1 | GLP-1R AGONISTS AND USES THEREOF | GLP1R, GPR119, GIPR | HTR2A 474/4885HTR2C 644/4885SLC6A4 2801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.