Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.64 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28695684 | 0.88 | TLR8 (0.62) | TLR8PDE10AKDM4EALDH1A1GAA | |
| SCHEMBL10641295 | 0.79 | L3MBTL1 (0.61) | TLR8PDE10AKDM4EALDH1A1GAA | |
| SCHEMBL31529366 | 0.79 | L3MBTL1 (0.61) | TLR8PDE10AKDM4EALDH1A1GAA | |
| SCHEMBL29366598 | 0.79 | PDE10A (0.59) | TLR8PDE10AKDM4EMEN1ALDH1A1 | |
| SCHEMBL16836411 | 0.78 | TLR8 (1.00) | TLR8 | |
| Hydrochloric Acid SCHEMBL9847504 | 0.75 | L3MBTL1 (0.60) | TLR8PDE10AKDM4EMEN1ALDH1A1 | |
| SCHEMBL29207050 | 0.74 | PDE10A (0.54) | TLR8PDE10AKDM4EMEN1ALDH1A1 | |
| SCHEMBL30060467 | 0.74 | MEN1 (0.61) | TLR8KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL4269051 | 0.74 | MEN1 (0.61) | TLR8KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL28214645 | 0.73 | PDE10A (0.57) | TLR8PDE10AKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121574128-A | Pyrimidine-hydroxamic acid compounds and uses thereof | 华东理工大学 | 2026-02-27 | — | — | CN | disclosed |
| US-12377079-B2 | Antibacterial compounds and uses thereof | THE CHILDREN'S MEDICAL CENTER CORPORATION | 2025-08-05 | — | — | US | disclosed |
| US-20250092471-A1 | METHODS AND REAGENTS FOR DETECTING PIPERAQUINE-RESISTANT PLASMODIUM FALCIPARUM MALARIA | INSTITUT PASTEUR (FR) | 2025-03-20 | — | — | US | disclosed |
| CN-119176840-A | Phosphorus-containing (meth) acryl composition, method for producing same, flame-retardant resin composition, prepreg, and use thereof | 日铁化学材料株式会社 | 2024-12-24 | — | — | CN | disclosed |
| US-12168805-B2 | Methods and reagents for detecting piperaquine-resistant plasmodium falciparum malaria | INSTITUT PASTEUR (FR) | 2024-12-17 | — | — | US | disclosed |
| US-20220023270-A1 | ANTIBACTERIAL COMPOUNDS AND USES THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2022-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12377079-B2 | Antibacterial compounds and uses thereof | CLPP, SPOUT1, MRPL21 | TLR8 82/4885PDE10A 2912/4885KDM4E 4451/4885 |
| US-20220023270-A1 | ANTIBACTERIAL COMPOUNDS AND USES THEREOF | CLPP, SPOUT1, MRPL21 | TLR8 82/4885PDE10A 2912/4885KDM4E 4451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.