Lysine

Lysine

SCHEMBL29361655

NCCCC[C@H](N)C(=O)[O-].[Cl-].[Mn+2]

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ GSR P00390 1/20 0.59
▸ GNAI3 P08754 1/20 0.42
▸ GNAO1 P09471 1/20 0.42
▸ GNAI1 P63096 1/20 0.42
▸ RNPEP Q9H4A4 1/20 0.42
▸ DPP7 Q9UHL4 10/20 0.41
▸ DPP8 Q6V1X1 5/20 0.41
▸ DPP9 Q86TI2 5/20 0.41
▸ DPP4 P27487 4/20 0.41
▸ CPB2 Q96IY4 2/20 0.38
▸ FAP Q12884 1/20 0.37
▸ MMP2 P08253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lysine SCHEMBL3749535 0.98 GSR (0.61) GSRGNAI3GNAO1GNAI1RNPEP
Lysine SCHEMBL3749539 0.98 GSR (0.61) GSRGNAI3GNAO1GNAI1RNPEP
Lysine SCHEMBL9767819 0.96 GSR (0.59) GSRGNAI3GNAO1GNAI1RNPEP
Lysine SCHEMBL7507173 0.94 GSR (0.57) GSRGNAI3GNAO1GNAI1RNPEP
Lysine SCHEMBL25283016 0.93 GSR (0.61) GSRGNAI3GNAO1GNAI1RNPEP
Lysine SCHEMBL121844 0.93 GSR (0.61) GSRGNAI3GNAO1GNAI1RNPEP
Lysine SCHEMBL4400353 0.93 GSR (0.61) GSRGNAI3GNAO1GNAI1RNPEP
Lysine SCHEMBL5691386 0.93 GSR (0.61) GSRGNAI3GNAO1GNAI1RNPEP
Lysine SCHEMBL3517540 0.93 GSR (0.61) GSRGNAI3GNAO1GNAI1RNPEP
Lysine SCHEMBL5148145 0.93 GSR (0.61) GSRGNAI3GNAO1GNAI1RNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260116846-A1 PREPARATION OF A LYSINATE COMPOUND FROM AN AQUEOUS LYSINE SOLUTION PHYTOBIOTICS FUTTERZUSATZSTOFFE GMBH (DE) 2026-04-30 — — US disclosed
US-12497350-B2 Preparation of a lysinate compound from an aqueous lysine solution PHYTOBIOTICS FUTTERZUSATZSTOFFE GMBH (DE) 2025-12-16 — — US disclosed
EP-3670494-B1 PRODUCTION OF LYSINATE COMPOUND FROM AN AQUEOUS LYSIN SOLUTION PHYTOBIOTICS FUTTERZUSATZSTOFFE GMBH (DE) 2023-06-14 — — EP disclosed
US-20220024856-A1 PREPARATION OF A LYSINATE COMPOUND FROM AN AQUEOUS LYSIN SOLUTION PHYTOBIOTICS FUTTERZUSATZSTOFFE GMBH (DE) 2022-01-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220024856-A1 PREPARATION OF A LYSINATE COMPOUND FROM AN AQUEOUS LYSIN SOLUTION LTN1, LCT, LPXN GSR 4803/4885GNAI3 4261/4885GNAO1 4080/4885
US-20260116846-A1 PREPARATION OF A LYSINATE COMPOUND FROM AN AQUEOUS LYSINE SOLUTION SLC6A9, SLC6A19, SLC39A14 GSR 4531/4885GNAI3 4664/4885GNAO1 4498/4885
US-12497350-B2 Preparation of a lysinate compound from an aqueous lysine solution KDM5A, KDM5B, KDM5C GSR 4835/4885GNAI3 4543/4885GNAO1 4308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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