SCHEMBL29362115

SCHEMBL29362115

CC(=O)NNC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 1.00
ALDH1A1 P00352 1/20 1.00
CYP1A2 P05177 1/20 1.00
CYP3A4 P08684 1/20 1.00
CYP2D6 P10635 1/20 1.00
MAPT P10636 1/20 1.00
ALOX15 P16050 1/20 1.00
CYP2C19 P33261 1/20 1.00
THPO P40225 1/20 1.00
PMP22 Q01453 1/20 1.00
KMT2A Q03164 1/20 1.00
PTGER2 P43116 4/20 0.70
PTGER1 P34995 8/20 0.69
HSD17B3 P37058 4/20 0.47
PGR P06401 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29829316 1.00 MEN1 (1.00) MEN1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL12648484 1.00 MEN1 (1.00) MEN1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL9857510 0.87 PTGER2 (0.80) MEN1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL11827815 0.86 MEN1 (0.76) MEN1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL11827802 0.86 MEN1 (0.76) MEN1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL11827339 0.86 ALDH1A1 (0.75) MEN1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL11832737 0.85 MAPT (0.74) MEN1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL9857831 0.85 ALDH1A1 (0.73) MEN1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL11839545 0.84 PTGER2 (0.79) MEN1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL11838052 0.84 MEN1 (0.72) MEN1ALDH1A1CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255969-A1 TARGETING IMMUNE PATHOLOGIES INDUCED BY HIGHLY PATHOGENIC CORONAVIRUSES NATIONAL UNIVERSITY OF SINGAPORE (SG) 2023-08-17 US claimed
EP-4185286-A1 TARGETING IMMUNE PATHOLOGIES INDUCED BY HIGHLY PATHOGENIC CORONAVIRUSES National University of Singapore (SG) 2023-05-31 EP claimed
WO-2022019828-A1 TARGETING IMMUNE PATHOLOGIES INDUCED BY HIGHLY PATHOGENIC CORONAVIRUSES NATIONAL UNIVERSITY OF SINGAPORE (SG) 2022-01-27 WO claimed
US-20250186415-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2025-06-12 US disclosed
US-20250041211-A1 OPHTHALMIC PREPARATION AND APPLICATION THEREOF IN TREATMENT OF PRESBYOPIA Eye Hospital, Wenzhou Medical University (CN) 2025-02-06 US disclosed
EP-4489858-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS Harrow IP, LLC (US) 2025-01-15 EP disclosed
EP-4489746-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS Harrow IP, LLC (US) 2025-01-15 EP disclosed
US-20240423970-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2024-12-26 US disclosed
US-12102628-B2 Composition and methods for the treatment of myopia Seinda Pharmaceutical Guangzhou Corporation 2024-10-01 US disclosed
EP-3654964-B1 COMPOSITION COMPRISING ATROPINE AND A MIOTIC AGENT AND ITS USE IN THE TREATMENT OF MYOPIA SEINDA PHARMACEUTICAL GUANGZHOU CORP (CN) 2024-04-24 EP disclosed
EP-3471722-B1 COMPOUNDS, COMPOSITIONS AND METHODS FOR PREVENTION AND/OR TREATMENT OF CANCER UNIV PENNSYLVANIA (US) 2023-10-25 EP disclosed
WO-2023172840-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS HARROW IP, LLC (US) 2023-09-14 WO disclosed
US-20230277521-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS HARROW IP, LLC 2023-09-07 US disclosed
US-20230255969-A1 TARGETING IMMUNE PATHOLOGIES INDUCED BY HIGHLY PATHOGENIC CORONAVIRUSES NATIONAL UNIVERSITY OF SINGAPORE (SG) 2023-08-17 US disclosed
EP-4185286-A1 TARGETING IMMUNE PATHOLOGIES INDUCED BY HIGHLY PATHOGENIC CORONAVIRUSES National University of Singapore (SG) 2023-05-31 EP disclosed
US-20230062844-A1 COMPOSITION AND METHODS FOR THE TREATMENT OF MYOPIA Seinda Pharmaceutical Guangzhou Corporation (CN) 2023-03-02 US disclosed
US-20220244263-A1 METHODS FOR TREATING SMALL CELL NEUROENDOCRINE AND RELATED CANCERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-08-04 US disclosed
US-11369618-B2 Compounds, compositions and methods for prevention and/or treatment of cancer THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2022-06-28 US disclosed
US-11285141-B2 Composition and methods for the treatment of myopia Seinda Pharmaceutical Guangzhou Corporation (CN) 2022-03-29 US disclosed
WO-2022019828-A1 TARGETING IMMUNE PATHOLOGIES INDUCED BY HIGHLY PATHOGENIC CORONAVIRUSES NATIONAL UNIVERSITY OF SINGAPORE (SG) 2022-01-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12102628-B2 Composition and methods for the treatment of myopia CHRM3, CHRM2, MYOC MEN1 698/4885ALDH1A1 3222/4885CYP1A2 3237/4885
US-11285141-B2 Composition and methods for the treatment of myopia CHRM3, CHRM2, MYOC MEN1 698/4885ALDH1A1 3222/4885CYP1A2 3237/4885
US-20230062844-A1 COMPOSITION AND METHODS FOR THE TREATMENT OF MYOPIA CHRM3, CHRM2, MYOC MEN1 698/4885ALDH1A1 3222/4885CYP1A2 3237/4885
US-11369618-B2 Compounds, compositions and methods for prevention and/or treatment of cancer GPER1, GPR3, GPR4 MEN1 1559/4885ALDH1A1 912/4885CYP1A2 2308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.