Alpha-Bungarotoxin

Alpha-Bungarotoxin

SCHEMBL29366348

C=C(C=O)C[C@H]1C[C@H](O)[C@]2(C)O[C@@H]3C[C@@H]4O[C@@H]5C[C@]6(C)O[C@]7(C)CC[C@@H]8O[C@@H]9C[C@]%10(C)O[C@@H]%11C(C)=CC(=O)O[C@H]%11C[C@H]%10O[C@H]9C[C@@H](C)[C@H]8O[C@H]7C[C@H]6O[C@@]5(C)C/C=C\[C@H]4O[C@H]3C[C@H]2O1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SCN1A P35498 1/20 1.00
SCN2A Q99250 1/20 1.00
SCN3A Q9NY46 1/20 1.00
ALDH1A1 P00352 4/20 0.87
NPSR1 Q6W5P4 3/20 0.87
MEN1 O00255 1/20 0.87
KMT2A Q03164 1/20 0.87
PDE4D Q08499 3/20 0.87
NPC1 O15118 2/20 0.86
MAPT P10636 2/20 0.86
MAPK1 P28482 2/20 0.86
RAB9A P51151 2/20 0.86
XBP1 P17861 1/20 0.86
POLB P06746 1/20 0.82
CRHBP P24387 1/20 0.78
CRHR2 Q13324 1/20 0.78
HTT P42858 1/20 0.43
ATM Q13315 1/20 0.43
RAP1A P62834 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alpha-Bungarotoxin SCHEMBL14043478 1.00 SCN1A (1.00) SCN1ASCN2ASCN3AALDH1A1NPSR1
Alpha-Bungarotoxin SCHEMBL29386702 1.00 SCN1A (1.00) SCN1ASCN2ASCN3AALDH1A1NPSR1
Brevetoxin B SCHEMBL869360 1.00 SCN1A (1.00) SCN1ASCN2ASCN3AALDH1A1NPSR1
Alpha-Bungarotoxin SCHEMBL29374938 1.00 SCN1A (1.00) SCN1ASCN2ASCN3AALDH1A1NPSR1
Alpha-Bungarotoxin SCHEMBL14106557 1.00 SCN1A (1.00) SCN1ASCN2ASCN3AALDH1A1NPSR1
Alpha-Bungarotoxin SCHEMBL29381923 1.00 SCN1A (1.00) SCN1ASCN2ASCN3AALDH1A1NPSR1
SCHEMBL15502881 0.94 ALDH1A1 (0.89) SCN1ASCN2ASCN3AALDH1A1NPSR1
SCHEMBL12908959 0.93 ALDH1A1 (0.91) SCN1ASCN2ASCN3AALDH1A1NPSR1
SCHEMBL10159481 0.93 ALDH1A1 (0.91) SCN1ASCN2ASCN3AALDH1A1NPSR1
SCHEMBL10130542 0.93 ALDH1A1 (0.87) SCN1ASCN2ASCN3AALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 422 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025226839-A2 AUF1 COMPOSITIONS AND METHODS FOR PROMOTING GENERATION OF NEUROMUSCULAR JUNCTIONS NEW YORK UNIVERSITY (US) 2025-10-30 WO claimed
US-20250163130-A1 LIGAND GATED ION CHANNELS AND METHODS OF USE SWITCH BIO, INC. 2025-05-22 US claimed
CN-119506289-A Aptamer combination suitable for single-cell sequencing and application of aptamer combination in construction of biliary tract cancer cell patterns 中国科学院杭州医学研究所 2025-02-25 CN claimed
CN-119212689-A Nicotinic acetylcholine receptor antagonists/blockers for increasing dopamine 张燕峰 2024-12-27 CN claimed
EP-4479421-A1 LIGAND GATED ION CHANNELS AND METHODS OF USE Trames Bio, Inc. (US) 2024-12-25 EP claimed
CN-119137143-A Ligand-gated ion channels and methods of use thereof 特拉梅斯生物股份有限公司 2024-12-13 CN claimed
EP-4319816-A1 ANTI-VENOM ANTIBODIES AND USES THEREOF Centivax, Inc. (US) 2024-02-14 EP claimed
WO-2024028324-A1 MOLECULES FOR THE PREVENTION AND TREATMENT OF NEUROMUSCULAR DISORDERS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2024-02-08 WO claimed
WO-2023209212-A1 NEUTRALISATION OF α-NEUROTOXINS USING HUMAN RECOMBINANT IGG ANTIBODIES DANMARKS TEKNISKE UNIVERSITET (DK) 2023-11-02 WO claimed
WO-2023212244-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS TESSELLATE THERAPEUTICS, INC. (US) 2023-11-02 WO claimed
CN-114354525-B Alpha-bungarotoxin detection probe and method for detecting alpha-bungarotoxin for non-diagnostic purpose 云南大学 2023-09-05 CN claimed
WO-2023159247-A1 LIGAND GATED ION CHANNELS AND METHODS OF USE TRAMES BIO, INC. (US) 2023-08-24 WO claimed
WO-2022217116-A1 ANTI-VENOM ANTIBODIES AND USES THEREOF CENTIVAX, INC. (US) 2022-10-13 WO claimed
CN-114354525-A Alpha-bungarotoxin detection probe and method for detecting alpha-bungarotoxin in non-diagnosis purpose 云南大学 2022-04-15 CN claimed
US-20260144801-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MUSCLE CONDITIONS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2026-05-28 US disclosed
EP-4746855-A1 FORMULATIONS AND USES OF ROCK2 INHIBITORS FOR ALS Graviton Bioscience BV (NL) 2026-05-27 EP disclosed
WO-2026104987-A1 REMIBRUTINIB FOR USE IN THE TREATMENT OF MYASTHENIA GRAVIS NOVARTIS AG (CH) 2026-05-21 WO disclosed
EP-3946411-A1 COMPOSITIONS AND METHODS FOR GENETICALLY-ENCODED HIGH VOLTAGE-ACTIVATED CALCIUM CHANNEL BLOCKERS USING ENGINEERED UBIQUITIN LIGASES The Trustees of Columbia University in the City of New York (US) 2022-02-09 EP disclosed
US-11236360-B2 Adeno-associated viruses engineered for selectable tropism REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2022-02-01 US disclosed
US-11235005-B2 Primed muscle progenitor cells and uses thereof PURDUE RESEARCH FOUNDATION (US) 2022-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250163130-A1 LIGAND GATED ION CHANNELS AND METHODS OF USE CACNB2, CHRNA2, HCN3 SCN1A 72/4885SCN2A 95/4885SCN3A 47/4885
US-20260144801-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MUSCLE CONDITIONS CPT1B, HPGD, PTGES SCN1A 2795/4885SCN2A 2899/4885SCN3A 2778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.