Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 1.00 |
| ▸ | SCN2A | Q99250 | 1/20 | 1.00 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.87 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.87 |
| ▸ | MEN1 | O00255 | 1/20 | 0.87 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.87 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.87 |
| ▸ | NPC1 | O15118 | 2/20 | 0.86 |
| ▸ | MAPT | P10636 | 2/20 | 0.86 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.86 |
| ▸ | RAB9A | P51151 | 2/20 | 0.86 |
| ▸ | XBP1 | P17861 | 1/20 | 0.86 |
| ▸ | POLB | P06746 | 1/20 | 0.82 |
| ▸ | CRHBP | P24387 | 1/20 | 0.78 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.78 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | RAP1A | P62834 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alpha-Bungarotoxin SCHEMBL14043478 | 1.00 | SCN1A (1.00) | SCN1ASCN2ASCN3AALDH1A1NPSR1 | |
| Alpha-Bungarotoxin SCHEMBL29366348 | 1.00 | SCN1A (1.00) | SCN1ASCN2ASCN3AALDH1A1NPSR1 | |
| Alpha-Bungarotoxin SCHEMBL29386702 | 1.00 | SCN1A (1.00) | SCN1ASCN2ASCN3AALDH1A1NPSR1 | |
| Alpha-Bungarotoxin SCHEMBL29374938 | 1.00 | SCN1A (1.00) | SCN1ASCN2ASCN3AALDH1A1NPSR1 | |
| Alpha-Bungarotoxin SCHEMBL14106557 | 1.00 | SCN1A (1.00) | SCN1ASCN2ASCN3AALDH1A1NPSR1 | |
| Alpha-Bungarotoxin SCHEMBL29381923 | 1.00 | SCN1A (1.00) | SCN1ASCN2ASCN3AALDH1A1NPSR1 | |
| SCHEMBL15502881 | 0.94 | ALDH1A1 (0.89) | SCN1ASCN2ASCN3AALDH1A1NPSR1 | |
| SCHEMBL12908959 | 0.93 | ALDH1A1 (0.91) | SCN1ASCN2ASCN3AALDH1A1NPSR1 | |
| SCHEMBL10159481 | 0.93 | ALDH1A1 (0.91) | SCN1ASCN2ASCN3AALDH1A1NPSR1 | |
| SCHEMBL10130542 | 0.93 | ALDH1A1 (0.87) | SCN1ASCN2ASCN3AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11779551-B1 | Antitoxins to brevetoxin | THE FLORIDA INTERNATIONAL UNIVERISTY BOARD OF TRUSTEES (US) | 2023-10-10 | — | — | US | claimed |
| CN-113332967-B | Trapezoidal polyether modified and cysteine terminated chromatographic stationary phase, preparation method and application | 常州工程职业技术学院 | 2023-04-07 | — | — | CN | claimed |
| CN-113332967-A | Trapezoidal polyether modified and cysteine terminated chromatographic stationary phase, preparation method and application | 常州工程职业技术学院 | 2021-09-03 | — | — | CN | claimed |
| US-12350260-B2 | Protease-activated receptor-2 inhibitors for the treatment of sensory neuropathy induced by a marine neurotoxic poisoning | UNIVERSITE DE BRETAGNE OCCIDENTALE (FR) | 2025-07-08 | — | — | US | disclosed |
| US-12351494-B1 | Harmful algae bloom mitigation system | FLORIDA GULF COAST UNIVERSITY BOARD OF TRUSTEES (US) | 2025-07-08 | — | — | US | disclosed |
| US-20250085274-A1 | BREVETOXIN DETECTION DEVICE, SYSTEM, AND METHOD | MOTE MARINE LABORATORY INC (US) | 2025-03-13 | — | — | US | disclosed |
| US-11779551-B1 | Antitoxins to brevetoxin | THE FLORIDA INTERNATIONAL UNIVERISTY BOARD OF TRUSTEES (US) | 2023-10-10 | — | — | US | disclosed |
| US-11760758-B2 | Mitragynine analogs for the treatment of pain, mood disorders and substance use disorders | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-09-19 | — | — | US | disclosed |
| CN-113332967-B | Trapezoidal polyether modified and cysteine terminated chromatographic stationary phase, preparation method and application | 常州工程职业技术学院 | 2023-04-07 | — | — | CN | disclosed |
| CN-111138447-B | B-group hapten, artificial antigen and monoclonal antibody of Gymnodinium breve toxin, and preparation method and application thereof | 国家海洋环境监测中心 | 2022-09-06 | — | — | CN | disclosed |
| US-20220193048-A1 | PROTEASE-ACTIVATED RECEPTOR-2 INHIBITORS FOR THE TREATMENT OF SENSORY NEUROPATHY INDUCED BY A MARINE NEUROTOXIC POISONING | UNIVERSITE DE BRETAGNE OCCIDENTALE (FR) | 2022-06-23 | — | — | US | disclosed |
| WO-2006003456-A2 | GLYCOSYLATION OF ANTIBIOTICS | ISIS INNOVATION LIMITED (GB) | 2006-01-12 | — | — | WO | disclosed |
| US-20050148041-A1 | Sandwich assay kits for detecting shigatoxin ctx3c | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2005-07-07 | — | — | US | disclosed |
| US-20050124686-A1 | Polyether brevetoxin derivatives as a treatment for cystic fibrosis, mucociliary dysfunction, and pulmonary diseases | UNIVERSITY OF NORTH CAROLINA (US) | 2005-06-09 | — | — | US | disclosed |
| US-20050124685-A1 | Polyether brevetoxin derivatives as a treatment for neurotoxic shellfish poisoning and ciguatera fish poisoning | UNIVERSITY OF NORTH CAROLINA AT WILMINGTON | 2005-06-09 | — | — | US | disclosed |
| WO-2005027903-A1 | POLYETHER BREVETOXIN DERIVATIVES AS A TREATMENT FOR NEUROTOXIC SHELLFISH POISONING AND CIGUATERA FISH POISONING | UNIVESITY OF NORTH CAROLINA AT (US) | 2005-03-31 | — | — | WO | disclosed |
| WO-2005028482-A1 | POLYETHER BREVETOXIN DERIVATIVES AS A TREATMENT FOR CYSTIC FIBROSIS, MUCOCILIARY DYSFUNCTION, AND PULMONARY DISEASES | UNIVERSITY OF NORTH CAROLINA AT WILMINGTON (US) | 2005-03-31 | — | — | WO | disclosed |
| US-20040077879-A1 | Bis (amino acid) molecular scaffolds | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2004-04-22 | — | — | US | disclosed |
| US-20040059096-A1 | Anti-ciguatoxin monoclonal antibody | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2004-03-25 | — | — | US | disclosed |
| WO-2004013282-A2 | BIS (AMINO ACID) MOLECULAR SCAFFOLDS | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2004-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040059096-A1 | Anti-ciguatoxin monoclonal antibody | PBK, IK, KLRK1 | SCN1A 3060/4885SCN2A 3327/4885SCN3A 3200/4885 |
| US-20040077879-A1 | Bis (amino acid) molecular scaffolds | DNPEP, BCAT1, BCAT2 | SCN1A 4111/4885SCN2A 2648/4885SCN3A 2740/4885 |
| US-20220193048-A1 | PROTEASE-ACTIVATED RECEPTOR-2 INHIBITORS FOR THE TREATMENT OF SENSORY NEUROPATHY INDUCED BY A MARINE NEUROTOXIC POISONING | PRSS12, TPSB2, F2RL1 | SCN1A 759/4885SCN2A 246/4885SCN3A 651/4885 |
| US-12350260-B2 | Protease-activated receptor-2 inhibitors for the treatment of sensory neuropathy induced by a marine neurotoxic poisoning | PRSS12, TPSB2, F2RL1 | SCN1A 759/4885SCN2A 246/4885SCN3A 651/4885 |
| US-11760758-B2 | Mitragynine analogs for the treatment of pain, mood disorders and substance use disorders | DRD2, OPRK1, OPRD1 | SCN1A 997/4885SCN2A 978/4885SCN3A 992/4885 |
| US-20050148041-A1 | Sandwich assay kits for detecting shigatoxin ctx3c | F13A1, HTR3D, INHA | SCN1A 2619/4885SCN2A 2164/4885SCN3A 235/4885 |
| US-20050124685-A1 | Polyether brevetoxin derivatives as a treatment for neurotoxic shellfish poisoning and ciguatera fish poisoning | ANTXR2, QRFPR, NPY2R | SCN1A 1011/4885SCN2A 886/4885SCN3A 375/4885 |
| US-11779551-B1 | Antitoxins to brevetoxin | ANTXR2, MTX1, TXN | SCN1A 3036/4885SCN2A 2703/4885SCN3A 1771/4885 |
| US-20050124686-A1 | Polyether brevetoxin derivatives as a treatment for cystic fibrosis, mucociliary dysfunction, and pulmonary diseases | CFTR, MUC1, SLC47A1 | SCN1A 1103/4885SCN2A 1760/4885SCN3A 788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.