Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10798879 | 0.86 | HTR7 (0.67) | HTR7RAB9ALMNASMN1; SMN2NPC1 | |
| SCHEMBL701534 | 0.84 | HTR7 (0.64) | HTR7RAB9ALMNASMN1; SMN2NPC1 | |
| SCHEMBL2344935 | 0.84 | HTR7 (0.64) | HTR7RAB9ALMNASMN1; SMN2NPC1 | |
| SCHEMBL2936738 | 0.84 | KDM4E (0.61) | RAB9ALMNASMN1; SMN2NPC1KDM4E | |
| SCHEMBL1458209 | 0.83 | KDM4E (0.68) | HTR7RAB9ALMNASMN1; SMN2NPC1 | |
| SCHEMBL1928374 | 0.83 | HTR7 (0.58) | HTR7RAB9ALMNASMN1; SMN2NPC1 | |
| SCHEMBL30883281 | 0.82 | HTR7 (0.62) | HTR7RAB9ALMNASMN1; SMN2NPC1 | |
| SCHEMBL11107067 | 0.82 | HTR7 (0.52) | HTR7RAB9ALMNASMN1; SMN2NPC1 | |
| SCHEMBL7912627 | 0.82 | LMNA (0.41) | HTR7RAB9ALMNASMN1; SMN2NPC1 | |
| SCHEMBL23630252 | 0.81 | HTR7 (0.56) | HTR7RAB9ALMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960884-A | Insecticides, nematocides, pesticides and miticides | FMC CORPORATION (US) | 1990-10-02 | — | — | US | claimed |
| US-12247027-B2 | P2X7 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2025-03-11 | — | — | US | disclosed |
| US-20240116930-A1 | P2X7 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-04-11 | — | — | US | disclosed |
| US-11820770-B2 | P2X7 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-21 | — | — | US | disclosed |
| US-11820770-B2 | P2X7 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-21 | — | — | US | disclosed |
| US-11820770-B2 | P2X7 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-21 | — | — | US | disclosed |
| US-11597733-B2 | Compounds and compositions for the treatment of parasitic diseases | NOVARTIS AG (CH) | 2023-03-07 | — | — | US | disclosed |
| US-20220213095-A1 | P2X7 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-07-07 | — | — | US | disclosed |
| US-20220213095-A1 | P2X7 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-07-07 | — | — | US | disclosed |
| US-11225478-B2 | P2X7 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2022-01-18 | — | — | US | disclosed |
| WO-2014152604-A1 | P2X7 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-09-25 | — | — | WO | disclosed |
| US-20140275015-A1 | P2X7 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-09-18 | — | — | US | disclosed |
| US-20140275015-A1 | P2X7 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-09-18 | — | — | US | disclosed |
| US-20140275015-A1 | P2X7 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-09-18 | — | — | US | disclosed |
| US-7928268-B2 | Process for producing 1,2-dialkoxy-3-fluorobenzene | ASAHI GLASS COMPANY, LIMITED (JP) | 2011-04-19 | — | — | US | disclosed |
| US-20100286451-A1 | Process for producing 1,2-dialkoxy-3-fluorobenzene | ASAHI GLASS COMPANY, LIMITED | 2010-11-11 | — | — | US | disclosed |
| US-7786330-B2 | sulfonation, halogenation, deprotection, with 2-fluorophenol as starting material; industrial scale | ASAHI GLASS COMPANY, LIMITED (JP) | 2010-08-31 | — | — | US | disclosed |
| US-20090227817-A1 | Process for producing 1,2-dialkoxy-3-fluorobenzene | ASAHI GLASS COMPANY, LIMITED | 2009-09-10 | — | — | US | disclosed |
| EP-2055692-A1 | PROCESS FOR PRODUCING 1,2-DIALKOXY-3-FLUOROBENZENE | Asahi Glass Co., Ltd. (JP) | 2009-05-06 | — | — | EP | disclosed |
| US-4960884-A | Insecticides, nematocides, pesticides and miticides | FMC CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227817-A1 | Process for producing 1,2-dialkoxy-3-fluorobenzene | HAAO, HDHD5, AFF2 | HTR7 1652/4885RAB9A 3261/4885LMNA 4340/4885 |
| US-12247027-B2 | P2X7 modulators | P2RX2, P2RX7, P2RY2 | HTR7 301/4885RAB9A 3242/4885LMNA 2272/4885 |
| US-11225478-B2 | P2X7 modulators | P2RX2, P2RX7, P2RY2 | HTR7 301/4885RAB9A 3242/4885LMNA 2272/4885 |
| US-11597733-B2 | Compounds and compositions for the treatment of parasitic diseases | ABCB11, SQLE, FURIN | HTR7 4195/4885RAB9A 1114/4885LMNA 1146/4885 |
| US-20100286451-A1 | Process for producing 1,2-dialkoxy-3-fluorobenzene | HAAO, HDHD5, AFF2 | HTR7 1652/4885RAB9A 3261/4885LMNA 4340/4885 |
| US-11820770-B2 | P2X7 modulators | P2RX2, P2RX7, P2RY2 | HTR7 301/4885RAB9A 3242/4885LMNA 2272/4885 |
| US-20220213095-A1 | P2X7 MODULATORS | P2RX2, P2RX7, P2RY2 | HTR7 301/4885RAB9A 3242/4885LMNA 2272/4885 |
| US-20240116930-A1 | P2X7 MODULATORS | P2RX2, P2RX7, P2RY2 | HTR7 301/4885RAB9A 3242/4885LMNA 2272/4885 |
| US-20140275015-A1 | P2X7 MODULATORS | P2RX2, P2RX7, P2RY2 | HTR7 301/4885RAB9A 3242/4885LMNA 2272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.