Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28166328 | 0.98 | CYP1A2 (0.55) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| SCHEMBL32667946 | 0.76 | PDGFRB (0.77) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| SCHEMBL2772360 | 0.76 | PDGFRB (0.77) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| SCHEMBL272937 | 0.74 | CYP1A2 (0.59) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| SCHEMBL27960103 | 0.74 | PDGFRB (0.67) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| Ethylene SCHEMBL28325267 | 0.74 | CYP1A2 (0.53) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| SCHEMBL271505 | 0.74 | CYP1A2 (0.53) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| SCHEMBL4818276 | 0.74 | ALDH1A1 (0.63) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| SCHEMBL438735 | 0.73 | CYP1A2 (0.57) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| SCHEMBL372216 | 0.73 | CYP1A2 (0.57) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2192 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271331-A | Gelsemin derivatives, synthesis method and application thereof in inhibiting tumor cell proliferation | 赣江中药创新中心 | 2024-07-02 | — | — | CN | claimed |
| CN-117946031-A | Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors | 北京大学 | 2024-04-30 | — | — | CN | claimed |
| WO-2023107630-A2 | AMINO ALCOHOL COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | claimed |
| EP-3542801-A1 | PURIN DERIVATIVES FOR USE IN THE TREATMENT OF FAP-RELATED DISEASES | Boehringer Ingelheim International GmbH (DE) | 2019-09-25 | — | — | EP | claimed |
| EP-3101017-B1 | 4'-O-SUBSTITUTED ISOINDOLINE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME | CELGENE CORP (US) | 2019-06-12 | — | — | EP | claimed |
| WO-2018102006-A1 | COMPOUNDS FOR THE INHIBITION OF INDOLEAMINE-2,3-DIOXYGENASE ACTIVITY AND USE THEREOF | ENSEMBLE THERAPEUTICS CORPORATION (US) | 2018-06-07 | — | — | WO | claimed |
| US-9539261-B2 | Methods and compositions for stimulating neurogenesis and inhibiting neuronal degeneration | NEURONASCENT, INC. (US) | 2017-01-10 | — | — | US | claimed |
| EP-3101017-A1 | 4'-O-SUBSTITUTED ISOINDOLINE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME | Celgene Corporation (US) | 2016-12-07 | — | — | EP | claimed |
| CN-102743382-B | Nerve is stimulated to be formed and the method and composition of inhibitory neuron degeneration | 诺伊罗纳森特公司 | 2016-12-07 | — | — | CN | claimed |
| EP-2142534-B1 | 4'-O-SUBSTITUTED ISOINDOLINE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME | CELGENE CORP (US) | 2016-08-10 | — | — | EP | claimed |
| EP-0863915-B1 | ACYLATED ENOL DERIVATIVES OF ALPHA-KETOESTERS AND ALPHA-KETOAMIDES | HOECHST MARION ROUSSEL INC (US) | 2000-02-02 | — | — | EP | claimed |
| US-5948886-A | ELASTASE INHIBITORS OR PRODRUGS; FOR TREATMENT OF EMPHYSEMA, CYSTIC FIBROSIS, ADULT RESPIRATORY DISTRESS SYNDROME, GOUT, DISSEMINATED INTRAVASCULAR COAGULATION, RHEUMATOID ARTHRITIS, CHRONIC BRONCHITIS, INFLAMMATORY BOWEL DISEASE, SEPTICEMIA | HOECHST MARION ROUSSEL, INC. (US) | 1999-09-07 | — | — | US | claimed |
| CN-1203602-A | Acylated enol derivatives of 'alpha'-ketoesters and 'alpha'-ketoamides | HOECHST MARION ROUSSEL INC (US) | 1998-12-30 | — | — | CN | claimed |
| EP-0863915-A1 | ACYLATED ENOL DERIVATIVES OF $g(a)-KETOESTERS AND $g(a)-KETOAMIDES | HOECHST MARION ROUSSEL, INC. (US) | 1998-09-16 | — | — | EP | claimed |
| CN-1172802-A | Process for preparation of [(5, 6 -dicarboxy 3 -pyridyl) methyl] ammonium halides | AMERICAN CYANAMID CO (US) | 1998-02-11 | — | — | CN | claimed |
| WO-1997020856-A1 | ACYLATED ENOL DERIVATIVES OF α-KETOESTERS AND α-KETOAMIDES | HOECHST MARION ROUSSEL, INC. (US) | 1997-06-12 | — | — | WO | claimed |
| WO-1996017862-A1 | LHRH ANTAGONISTS HAVING LACTAM GROUPS AT THE N-TERMINUS | ABBOTT LABORATORIES (US) | 1996-06-13 | — | — | WO | claimed |
| US-5516759-A | LHRH antagonists having lactam groups at the N-terminus | TAP HOLDINGS INC. (US) | 1996-05-14 | — | — | US | claimed |
| EP-0190946-B1 | NOVEL CYCLIC HEXAPEPTIDE LHRH ANTAGONISTS | MERCK & CO. INC. (US) | 1993-01-20 | — | — | EP | claimed |
| EP-0190946-A2 | Novel cyclic hexapeptide LHRH antagonists | MERCK & CO. INC. (US) | 1986-08-13 | — | — | EP | claimed |