SCHEMBL29370211

SCHEMBL29370211

CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](C)N)[C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CAPN1 P07384 4/20 0.64
▸ CTSB P07858 2/20 0.64
▸ NTSR2 O95665 3/20 0.60
▸ NTSR1 P30989 3/20 0.60
▸ SORT1 Q99523 2/20 0.60
▸ KISS1R Q969F8 4/20 0.56
▸ GNRHR P30968 1/20 0.56
▸ ABCC2 Q92887 1/20 0.55
▸ TACR1 P25103 1/20 0.55
▸ PTGS1 P23219 1/20 0.54
▸ F13A1 P00488 1/20 0.52
▸ TGM2 P21980 1/20 0.52
▸ DPP3 Q9NY33 2/20 0.51
▸ C5AR1 P21730 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29463717 0.91 CAPN1 (0.63) CAPN1CTSBNTSR2NTSR1SORT1
SCHEMBL29463744 0.88 KISS1R (0.60) CAPN1CTSBNTSR2NTSR1SORT1
SCHEMBL31332280 0.84 KISS1R (0.64) NTSR2NTSR1SORT1KISS1RGNRHR
SCHEMBL31331997 0.83 KISS1R (0.62) NTSR2NTSR1SORT1KISS1RGNRHR
SCHEMBL38652302 0.83 CXCR4 (0.59) CAPN1CTSBNTSR2NTSR1SORT1
SCHEMBL29716634 0.83 NTSR2 (0.75) NTSR2NTSR1SORT1GNRHRABCC2
SCHEMBL30659714 0.83 CAPN1 (0.66) CAPN1CTSBNTSR2NTSR1SORT1
SCHEMBL29598567 0.82 KISS1R (0.65) NTSR2NTSR1KISS1RTACR1C5AR1
SCHEMBL32681271 0.82 DPP3 (0.66) CAPN1CTSBNTSR2NTSR1SORT1
SCHEMBL29772142 0.82 KISS1R (0.64) NTSR2NTSR1SORT1KISS1RABCC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118557735-A Application of NRP1 inhibitor in preparation of anti-vascular calcification medicine 中山大学附属第八医院(深圳福田) 2024-08-30 — — CN claimed
CN-117562995-A Nanometer medicine for synergistic chemophotothermal therapy and targeted treatment of endometriosis and preparation method thereof 无锡市中医医院 2024-02-20 — — CN claimed
CN-116688164-A Radionuclide-labeled A7R polypeptides D A7R polypeptide and application thereof 上海市第一人民医院 2023-09-05 — — CN claimed
CN-115518152-B Polypeptide micelle for enhancing light immunotherapy based on tumor vascular normalization and immune checkpoint blocking and preparation and application thereof 中山大学 2023-09-01 — — CN claimed
CN-115611988-A Compounds for targeted immunotherapy 博笛生物科技有限公司 2023-01-17 — — CN claimed
CN-115518152-A Polypeptide micelle for enhancing photoimmunotherapy based on tumor blood vessel normalization and immune checkpoint blockade coordination, and preparation and application thereof 中山大学 2022-12-27 — — CN claimed
CN-115521369-A Biomarker NRP1 and application thereof in diagnosis, prevention and treatment of pulmonary fibrosis and asthma 上海市免疫学研究所 2022-12-27 — — CN claimed
CN-115337402-A Combination therapeutic compositions and combination therapeutic methods for treating cancer 博笛生物科技有限公司 2022-11-15 — — CN claimed
US-20220322945-A1 USE OF FLUOROPHORE COMPOUNDS OF THE AZA- BODIPY TYPE AS CONTRAST AGENTS IN THE SHORT WAVE INFRARED REGION INSERM - INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (FR) 2022-10-13 — — US claimed
EP-4010434-A1 USE OF FLUOROPHORE COMPOUNDS OF THE AZA-BODIPY TYPE AS CONTRAST AGENTS IN THE SHORT WAVE INFRARED REGION UNIVERSITE GRENOBLE ALPES (FR) 2022-06-15 — — EP claimed
CN-114450353-A Use of aza-fluoroboro-fluorescent fluorophore compounds as contrast agents in the short-wave infrared region 阿尔卑斯格勒诺布尔大学 2022-05-06 — — CN claimed
CN-122031708-A Cascade double-and logic DNA nano circuit and preparation method and application thereof 南方医科大学珠江医院 2026-05-15 — — CN disclosed
CN-121971585-A Application of micromolecular drug ATWLPPR PEPTIDE TFA in resisting mycobacterium bovis infection 中国农业科学院哈尔滨兽医研究所(中国动物卫生与流行病学中心哈尔滨分中心) 2026-05-05 — — CN disclosed
CN-121971585-A Application of micromolecular drug ATWLPPR PEPTIDE TFA in resisting mycobacterium bovis infection 中国农业科学院哈尔滨兽医研究所(中国动物卫生与流行病学中心哈尔滨分中心) 2026-05-05 — — CN disclosed
US-12590122-B2 NRP-1 binding inhibitory peptides and uses thereof INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2026-03-31 — — US disclosed
US-20220064671-A1 METHODS AND SYSTEMS FOR PRODUCING AAV PARTICLES VOYAGER THERAPEUTICS INC (US) 2022-03-03 — — US disclosed
US-11260133-B2 Methods and compositions related to peptides and proteins with C-terminal elements SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) 2022-03-01 — — US disclosed
US-11260032-B2 Method for preparing biofilm-coated drug nanocrystal and application thereof Shanghai Whittlong Pharmaceutical Institute (CN) 2022-03-01 — — US disclosed
WO-2022026409-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS RELATED TO GLUCOSYLCERAMIDASE BETA DEFICIENCY VOYAGER THERAPEUTICS, INC. (US) 2022-02-03 — — WO disclosed
WO-2022026410-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF NIEMANN-PICK TYPE C1 DISEASE VOYAGER THERAPEUTICS, INC (US) 2022-02-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11260133-B2 Methods and compositions related to peptides and proteins with C-terminal elements CD2BP2, CLTC, CLTA CAPN1 444/4885CTSB 331/4885NTSR2 674/4885
US-12590122-B2 NRP-1 binding inhibitory peptides and uses thereof NRP1, FLT1, KDR CAPN1 2238/4885CTSB 3288/4885NTSR2 62/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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