SCHEMBL29370428

SCHEMBL29370428

O=C(N[C@@H](Cc1ccc2ccccc2c1)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 3/20 0.52
TP53 P04637 3/20 0.52
ACE P12821 4/20 0.50
MME P08473 3/20 0.50
CPA1 P15085 2/20 0.50
ACE2 Q9BYF1 2/20 0.50
CTSL P07711 1/20 0.50
CTSB P07858 1/20 0.50
CTSS P25774 1/20 0.50
PTPN1 P18031 2/20 0.48
MDM2 Q00987 2/20 0.48
CASP3 P42574 2/20 0.48
CA2 P00918 1/20 0.47
SLC17A5 Q9NRA2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL799706 1.00 MDM4 (0.52) MDM4TP53ACEMMECPA1
SCHEMBL29385767 1.00 MDM4 (0.52) MDM4TP53ACEMMECPA1
SCHEMBL1514663 1.00 MDM4 (0.52) MDM4TP53ACEMMECPA1
SCHEMBL29406248 1.00 MDM4 (0.52) MDM4TP53ACEMMECPA1
SCHEMBL29410226 1.00 MDM4 (0.52) MDM4TP53ACEMMECPA1
SCHEMBL3736523 1.00 MDM4 (0.52) MDM4TP53ACEMMECPA1
SCHEMBL29400401 1.00 MDM4 (0.52) MDM4TP53ACEMMECPA1
SCHEMBL29754274 0.97 MDM4 (0.52) MDM4TP53ACEMMECPA1
SCHEMBL8248794 0.92 MDM4 (0.49) MDM4TP53PTPN1MDM2CASP3
SCHEMBL15697341 0.90 CTSB (0.49) MDM4TP53CTSLCTSBCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4622991-A2 SYNTHESIS OF A CYCLIC PEPTIDE Janssen Pharmaceutica NV (BE) 2025-10-01 EP claimed
US-20250090698-A1 SMALL MOLECULE INHIBITORS FOR EARLY DIAGNOSIS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN CANCERS AND NEURODEGENERATIVE DISEASES INDIAN INSTITUTE OF TECH INDORE (IN) 2025-03-20 US claimed
WO-2024110477-A2 SYNTHESIS OF A CYCLIC PEPTIDE JANSSEN PHARMACEUTICA NV (BE) 2024-05-30 WO claimed
CN-116655516-A Compound for prostate cancer specific fluorescent probe, preparation method and application thereof 中国医学科学院肿瘤医院深圳医院 2023-08-29 CN claimed
CN-115925586-A Preparation method of parent of targeting PSMA and derivative thereof 青岛蓝谷多肽生物医药科技有限公司 2023-04-07 CN claimed
CN-114634425-A Novel synthesis process of PSMA inhibitor 湖北强耀生物科技有限公司 2022-06-17 CN claimed
CN-110898233-B Three-modal prostate cancer targeted nanoparticle imaging agent and preparation method thereof 北京肿瘤医院(北京大学肿瘤医院) 2022-04-05 CN claimed
US-20260139257-A1 PLIN1 RNAi INTERFERENCE AGENTS ELI LILLY AND CO (US) 2026-05-21 US disclosed
WO-2026098617-A1 RADIOPHARMACEUTICAL TARGETING CARBONIC ANHYDRASE IX PROTEIN 无锡诺宇医药科技有限公司 2026-05-15 WO disclosed
US-20260131034-A1 RADIOPHARMACEUTICALS TARGETING CARBONIC ANHYDRASE IX PROTEINS NORROY BIOSCIENCE CO LTD (CN) 2026-05-14 US disclosed
US-20260124313-A1 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN UNIV CALIFORNIA (US) 2026-05-07 US disclosed
US-12616761-B2 CXCR4-targeting compounds THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2026-05-05 US disclosed
US-12612343-B2 PSMA binder and use thereof Shiya Pharmaceutical, Inc (CN) 2026-04-28 US disclosed
EP-3723815-B1 PSMA LIGANDS FOR IMAGING AND ENDORADIOTHERAPY UNIV MUENCHEN TECH (DE) 2022-04-20 EP disclosed
CN-114364690-A Novel radiolabeled CXCR4 targeting compounds for diagnosis and therapy 省卫生服务机构 2022-04-15 CN disclosed
CN-110898233-B Three-modal prostate cancer targeted nanoparticle imaging agent and preparation method thereof 北京肿瘤医院(北京大学肿瘤医院) 2022-04-05 CN disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
EP-3956346-A1 NOVEL RADIOLABELLED CXCR4-TARGETING COMPOUNDS FOR DIAGNOSIS AND THERAPY Provincial Health Services Authority (CA) 2022-02-23 EP disclosed
EP-3554559-B1 METHOD FOR LABELING OF SENSITIVE AND THERMOSENSITIVE TARGETING BIOMOLECULES WITH TECHNETIUM BASED COMPOUNDS BRACCO IMAGING SPA (IT) 2022-02-02 EP disclosed
WO-2022018264-A1 SILICON-CONTAINING LIGAND COMPOUNDS Technische Universität München (DE) 2022-01-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260131034-A1 RADIOPHARMACEUTICALS TARGETING CARBONIC ANHYDRASE IX PROTEINS CA9, CA11, CA12 MDM4 4599/4885TP53 3128/4885ACE 1415/4885
US-20260124313-A1 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN GLP1R, ALB, GIPR MDM4 4874/4885TP53 2182/4885ACE 1725/4885
US-12616761-B2 CXCR4-targeting compounds CXCR4, CXCR2, CXCR3 MDM4 3817/4885TP53 1733/4885ACE 4450/4885
US-20250090698-A1 SMALL MOLECULE INHIBITORS FOR EARLY DIAGNOSIS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN CANCERS AND NEURODEGENERATIVE DISEASES KLK3, SPAG5, DNPEP MDM4 2431/4885TP53 195/4885ACE 1091/4885
US-20260139257-A1 PLIN1 RNAi INTERFERENCE AGENTS PLIN1, PLIN3, PLIN5 MDM4 3255/4885TP53 4176/4885ACE 4562/4885
US-12612343-B2 PSMA binder and use thereof KLK3, AR, PSMA1 MDM4 3499/4885TP53 566/4885ACE 1449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.