SCHEMBL29371375

SCHEMBL29371375

CCCC[C@H](NC(=O)[C@@H](N)CCC(=O)O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NOD1 Q9Y239 7/20 0.56
▸ DPP8 Q6V1X1 5/20 0.53
▸ DPP9 Q86TI2 5/20 0.53
▸ DPP4 P27487 3/20 0.53
▸ DPP7 Q9UHL4 5/20 0.49
▸ FOLH1 Q04609 2/20 0.49
▸ PLA2G2C Q5R387 1/20 0.48
▸ RIMKLA Q8IXN7 1/20 0.47
▸ NAALAD2 Q9Y3Q0 1/20 0.47
▸ GRM8 O00222 1/20 0.47
▸ GRM6 O15303 1/20 0.47
▸ GRIN2D O15399 1/20 0.47
▸ GRIN3B O60391 1/20 0.47
▸ GSR P00390 1/20 0.47
▸ CYP1A2 P05177 1/20 0.47
▸ GRIK1 P39086 1/20 0.47
▸ GRM5 P41594 1/20 0.47
▸ GRIA1 P42261 1/20 0.47
▸ GRIA2 P42262 1/20 0.47
▸ GRIA3 P42263 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29843198 1.00 NOD1 (0.56) NOD1DPP8DPP9DPP4DPP7
SCHEMBL29376967 0.97 NOD1 (0.53) NOD1DPP8DPP9DPP4DPP7
SCHEMBL31674332 0.96 NOD1 (0.52) NOD1DPP8DPP9DPP4DPP7
SCHEMBL29382412 0.94 NOD1 (0.55) NOD1DPP8DPP9DPP4DPP7
SCHEMBL29382397 0.93 NOD1 (0.54) NOD1DPP8DPP9DPP4DPP7
SCHEMBL29684179 0.91 NOD1 (0.52) NOD1DPP8DPP9DPP4DPP7
SCHEMBL8495650 0.90 DPP4 (0.55) NOD1DPP8DPP9DPP4DPP7
SCHEMBL17941535 0.90 DPP4 (0.55) NOD1DPP8DPP9DPP4DPP7
SCHEMBL2850058 0.90 DPP7 (0.58) NOD1DPP8DPP9DPP4DPP7
SCHEMBL29376792 0.90 DPP7 (0.58) NOD1DPP8DPP9DPP4DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226225-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2024-07-11 — — US claimed
US-20240209053-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2024-06-27 — — US claimed
CN-117813313-A Binding hepcidin mimetics 领导医疗有限公司 2024-04-02 — — CN claimed
CN-117730089-A Binding hepcidin mimetics 领导医疗有限公司 2024-03-19 — — CN claimed
US-20240066131-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2024-02-29 — — US claimed
EP-4314017-A1 CONJUGATED HEPCIDIN MIMETICS Protagonist Therapeutics, Inc. (US) 2024-02-07 — — EP claimed
US-20240018189-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2024-01-18 — — US claimed
CN-117136192-A Conjugated hepcidin mimetics 领导医疗有限公司 2023-11-28 — — CN claimed
US-20230295259-A1 Conjugated Hepcidin Mimetics PROTAGONIST THERAPEUTICS, INC. 2023-09-21 — — US claimed
US-11753443-B2 Conjugated hepcidin mimetics PROTAGONIST THERAPEUTICS, INC. (US) 2023-09-12 — — US claimed
CN-116457000-A Conjugated hepcidin mimetics 普罗塔格尼斯特治疗股份有限公司 2023-07-18 — — CN claimed
EP-4188413-A1 CONJUGATED HEPCIDIN MIMETICS Protagonist Therapeutics, Inc. (US) 2023-06-07 — — EP claimed
EP-4188412-A1 CONJUGATED HEPCIDIN MIMETICS Protagonist Therapeutics, Inc. (US) 2023-06-07 — — EP claimed
WO-2022212696-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2022-10-06 — — WO claimed
WO-2022026631-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2022-02-03 — — WO claimed
WO-2022026633-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2022-02-03 — — WO claimed
WO-2022026629-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2022-02-03 — — WO claimed
US-20250304624-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. 2025-10-02 — — US disclosed
WO-2022026631-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2022-02-03 — — WO disclosed
WO-2022026629-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2022-02-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018189-A1 CONJUGATED HEPCIDIN MIMETICS HAMP, VIP, HDGF NOD1 1407/4885DPP8 863/4885DPP9 752/4885
US-20230295259-A1 Conjugated Hepcidin Mimetics HAMP, VIP, HDGF NOD1 1407/4885DPP8 863/4885DPP9 752/4885
US-11753443-B2 Conjugated hepcidin mimetics HAMP, VIP, HDGF NOD1 1407/4885DPP8 863/4885DPP9 752/4885
US-20240066131-A1 CONJUGATED HEPCIDIN MIMETICS HAMP, VIP, HDGF NOD1 1407/4885DPP8 863/4885DPP9 752/4885
US-20250304624-A1 CONJUGATED HEPCIDIN MIMETICS HAMP, VIP, HDGF NOD1 1407/4885DPP8 863/4885DPP9 752/4885
US-20240226225-A1 CONJUGATED HEPCIDIN MIMETICS HAMP, SLC40A1, FTH1 NOD1 1343/4885DPP8 2365/4885DPP9 2380/4885
US-20240209053-A1 CONJUGATED HEPCIDIN MIMETICS HAMP, SLC40A1, FTH1 NOD1 1326/4885DPP8 1928/4885DPP9 1899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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