SCHEMBL2937206

SCHEMBL2937206

C=C(CCC(=O)O)C(=O)OC(=O)C(=C)CCC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.47
EGLN1 Q9GZT9 5/20 0.47
ALKBH5 Q6P6C2 1/20 0.47
SUCNR1 Q9BXA5 1/20 0.47
SLC15A2 Q16348 1/20 0.38
MAPK1 P28482 1/20 0.38
SLC13A3 Q8WWT9 1/20 0.38
OR51E2 Q9H255 1/20 0.38
SLC22A6 Q4U2R8 1/20 0.36
TSHR P16473 2/20 0.35
NFKB1 P19838 1/20 0.35
PMP22 Q01453 1/20 0.35
KDM5C P41229 4/20 0.35
PHF8 Q9UPP1 4/20 0.35
KDM2A Q9Y2K7 4/20 0.35
KDM6B O15054 3/20 0.35
KDM4E B2RXH2 3/20 0.35
FOLH1 Q04609 1/20 0.35
GABRR1 P24046 1/20 0.35
FFAR3 O14843 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16415713 0.85 LMNA (0.52) LMNAOR51E2SLC22A6TSHRNFKB1
SCHEMBL16415705 0.85 SLC22A6 (0.52) LMNAEGLN1ALKBH5SUCNR1SLC22A6
SCHEMBL7039729 0.80 ALDH1A1 (0.44) LMNAEGLN1ALKBH5SUCNR1SLC15A2
SCHEMBL22643409 0.78 LMNA (0.41) LMNAEGLN1ALKBH5SUCNR1SLC15A2
SCHEMBL2484913 0.78 EGLN1 (0.36) LMNAEGLN1ALKBH5SUCNR1SLC15A2
SCHEMBL19278925 0.77 EGLN1 (0.39) LMNAEGLN1ALKBH5SUCNR1SLC15A2
SCHEMBL6023253 0.77 ALDH1A1 (0.45) LMNAEGLN1ALKBH5SUCNR1SLC15A2
SCHEMBL25232 0.76 ALOX15 (0.46) EGLN1FFAR3HSD17B10
SCHEMBL9868910 0.76
SCHEMBL7537722 0.75 EGLN1 (0.38) LMNAEGLN1ALKBH5SUCNR1SLC15A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3024873-A1 POLYMERIC SURFACTANT Huntsman Petrochemical LLC (US) 2016-06-01 EP disclosed
US-20160145382-A1 POLYMERIC SURFACTANT HUNTSMAN PETROCHEMICAL LLC 2016-05-26 US disclosed
WO-2015013011-A1 POLYMERIC SURFACTANT HUNTSMAN PETROCHEMICAL LLC (US) 2015-01-29 WO disclosed
EP-1582346-B1 Infrared absorbing compounds and their use in imageable elements EASTMAN KODAK CO (US) 2010-09-22 EP disclosed
US-7049046-B2 Infrared absorbing compounds and their use in imageable elements EASTMAN KODAK COMPANY (US) 2006-05-23 US disclosed
US-20050221215-A1 Infrared absorbing compounds and their use in imageable elements CITICORP NORTH AMERICA, INC., AS AGENT 2005-10-06 US disclosed
EP-1582346-A2 Infrared absorbing compounds and their use in imageable elements Kodak Polychrome Graphics, LLC (US) 2005-10-05 EP disclosed
US-4826980-A HYPOTENSIVE AGENTS HOFFMANN-LA ROCHE INC. (US) 1989-05-02 US disclosed
US-4785093-A Bicyclic compounds HOFFMANN-LA ROCHE INC. (US) 1988-11-15 US disclosed
US-4762924-A HYPOTENSIVE AGENTS HOFFMANN-LA ROCHE INC. (US) 1988-08-09 US disclosed
US-4743687-A HYPOTENSIVE AGENTS HOFFMANN-LA ROCHE INC. (US) 1988-05-10 US disclosed
US-4692438-A Pyridazo-diazepines, diazocines, and -triazepines having anti-hypertensive activity HOFFMANN-LA ROCHE INC. (US) 1987-09-08 US disclosed
US-3959521-A UNSATURATED ISOCYANATE UNDERCOATING, UNSATURATED RESIN OVERCOATING MITSUBISHI RAYON CO., LTD. (JA) 1976-05-25 US disclosed