SCHEMBL29372256

SCHEMBL29372256

CC1(CNC(=O)c2ccc(-c3ccc(Br)cc3)cc2)NC(=O)NC1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADAMTS7 Q9UKP4 2/20 0.52
ADAM17 P78536 1/20 0.48
ADAMTS5 Q9UNA0 3/20 0.47
ADAMTS4 O75173 2/20 0.47
MMP2 P08253 3/20 0.46
MMP13 P45452 2/20 0.46
MMP3 P08254 1/20 0.46
MMP12 P39900 1/20 0.46
OPRM1 P35372 2/20 0.45
OPRD1 P41143 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.41
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.41
POLB P06746 1/20 0.41
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ABL1 P00519 1/20 0.40
BCR P11274 1/20 0.40
OGG1 O15527 1/20 0.40
HPGD P15428 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12416690 0.88 ADAM17 (0.57) ADAMTS7ADAM17ADAMTS5ADAMTS4MMP2
SCHEMBL29658843 0.84 ADAM17 (0.40) ADAMTS7ADAM17ADAMTS5ADAMTS4MMP2
SCHEMBL29494606 0.84 ADAMTS5 (0.39) ADAMTS7ADAM17ADAMTS5ADAMTS4MMP2
SCHEMBL12378634 0.78 ADAM17 (0.56) ADAMTS7ADAM17ADAMTS5ADAMTS4MMP2
SCHEMBL4056808 0.78 ADAM17 (0.62) ADAM17ADAMTS5ADAMTS4MMP2MMP13
SCHEMBL30023704 0.74 CTSB (0.45) ADAMTS7ADAM17ADAMTS5ADAMTS4MMP2
SCHEMBL12378827 0.74 ADAMTS5 (0.46) ADAM17ADAMTS5ADAMTS4MMP2MMP13
SCHEMBL3247075 0.71 ADAMTS5 (0.48) ADAMTS7ADAM17ADAMTS5ADAMTS4MMP2
SCHEMBL23354303 0.71 ADAMTS5 (0.51) ADAMTS7ADAM17ADAMTS5ADAMTS4MMP2
SCHEMBL23354305 0.70 ADAMTS7 (0.69) ADAMTS7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4576552-A1 POWER CONVERTER Delta Electronics, Inc. (TW) 2025-06-25 EP claimed
CN-119909064-A Cystamine derivative or salt thereof and application thereof in preparation of medicines with antioxidation effect 北京大学深圳研究生院 2025-05-02 CN claimed
CN-119399026-A Remote sensing image super-resolution method, system and equipment based on implicit neural representation 浙江大学 2025-02-07 CN claimed
CN-118965298-B Natural gas flow prediction method and system based on model fusion and electronic equipment 杭州电子科技大学 2024-12-31 CN claimed
CN-118965298-A Natural gas flow prediction method and system based on model fusion and electronic equipment 杭州电子科技大学 2024-11-15 CN claimed
CN-114131601-B Cartesian trajectory tracking inverse kinematics algorithm for offset wrist 6R industrial manipulator 武汉科技大学 2024-07-30 CN claimed
US-20240251664-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-25 US claimed
CN-116949052-A Viral vectors encoding recombinant FVIII variants with increased expression for gene therapy of hemophilia a 武田药品工业株式会社 2023-10-27 CN claimed
CN-116479001-A Viral vectors encoding recombinant FVIII variants with increased expression for gene therapy of hemophilia a 武田药品工业株式会社 2023-07-25 CN claimed
CN-109741402-B Small-coincidence-field multi-camera combined calibration method based on laser radar 上海交通大学 2023-04-07 CN claimed
CN-115093997-A Microbial agent for treating crop fusarium wilt and verticillium wilt 柴天领 2022-09-23 CN claimed
CN-113285529-B Cascade type multi-source multi-load power supply method based on wireless power transmission 国网福建省电力有限公司电力科学研究院 2022-07-05 CN claimed
EP-3986481-A2 METHOD OF TREATMENT WITH VIRAL-BASED GENE THERAPY Takeda Pharmaceutical Company Limited (JP) 2022-04-27 EP claimed
CN-114375205-A Methods of treatment with virus-based gene therapy 武田药品工业株式会社 2022-04-19 CN claimed
CN-111384840-B Desk lamp power supply management circuit compatible with multiple voltage supplies and control method 浙江凯耀照明有限责任公司 2022-03-11 CN claimed
CN-114131601-A Cartesian locus tracking inverse kinematics algorithm for offset wrist 6R industrial manipulator 武汉科技大学 2022-03-04 CN claimed
CN-215778035-U Portable head-mounted blood oxygen and heart rate monitoring device 江西国科美信医疗科技有限公司 2022-02-11 CN claimed
CN-113554992-B Power voltage generator SAMSUNG DISPLAY CO.,LTD. (KR) 2026-05-26 CN disclosed
CN-215778035-U Portable head-mounted blood oxygen and heart rate monitoring device 江西国科美信医疗科技有限公司 2022-02-11 CN disclosed
US-11242964-B2 Illumination apparatus for simulating blue sky PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2022-02-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240251664-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME NES, NFE2L2, NUCB2 ADAMTS7 4880/4885ADAM17 3902/4885ADAMTS5 4872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.