Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIOK2 | Q9BVS4 | 6/20 | 0.62 |
| ▸ | GSK3A | P49840 | 3/20 | 0.62 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.62 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.62 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.62 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28692611 | 1.00 | RIOK2 (0.62) | RIOK2GSK3AMAPK10MAPK8HIPK1 | |
| SCHEMBL26158313 | 0.79 | RIOK2 (0.54) | RIOK2GSK3AMAPK10MAPK8HIPK1 | |
| SCHEMBL29124508 | 0.77 | RAB9A (0.63) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL30594478 | 0.77 | RAB9A (0.63) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL28692610 | 0.77 | ALDH1A1 (0.62) | MAPK10MAPK8L3MBTL1KMT2AMEN1 | |
| SCHEMBL13067797 | 0.75 | RIOK2 (0.54) | RIOK2GSK3AMAPK10MAPK8HIPK1 | |
| SCHEMBL27907868 | 0.75 | KMT2A (0.55) | L3MBTL1KMT2AMEN1KDM4EANO1 | |
| SCHEMBL30071338 | 0.74 | RAB9A (0.59) | L3MBTL1KMT2AMEN1KDM4E | |
| SCHEMBL2038480 | 0.74 | L3MBTL1 (0.76) | RIOK2GSK3AMAPK10MAPK8HIPK1 | |
| SCHEMBL4572346 | 0.74 | RAB9A (0.59) | L3MBTL1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114014803-A | Method for synthesizing urea compound by amidation reaction of amide and amine at room temperature | 内蒙古师范大学 | 2022-02-08 | — | — | CN | disclosed |