Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 10/20 | 0.89 |
| ▸ | MAPT | P10636 | 7/20 | 0.89 |
| ▸ | HPGD | P15428 | 6/20 | 0.89 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.89 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.89 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.89 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.89 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.89 |
| ▸ | TP53 | P04637 | 4/20 | 0.89 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.89 |
| ▸ | MEN1 | O00255 | 2/20 | 0.89 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.89 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.89 |
| ▸ | MAOA | P21397 | 2/20 | 0.89 |
| ▸ | MAOB | P27338 | 2/20 | 0.89 |
| ▸ | IKBKB | O14920 | 1/20 | 0.89 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.89 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 7,8-Dihydroxyflavone SCHEMBL29374601 | 0.94 | TERT (1.00) | TERTMAPTHPGDKDM4ECYP19A1 | |
| 7,8-Dihydroxyflavone SCHEMBL419316 | 0.94 | TERT (1.00) | TERTMAPTHPGDKDM4ECYP19A1 | |
| 7,8-Dihydroxyflavone SCHEMBL21852713 | 0.93 | TERT (0.97) | TERTMAPTHPGDKDM4ECYP19A1 | |
| SCHEMBL4649959 | 0.82 | TERT (1.00) | TERTMAPTHPGDKDM4ECYP19A1 | |
| SCHEMBL31322174 | 0.82 | TERT (1.00) | TERTMAPTHPGDKDM4ECYP19A1 | |
| SCHEMBL4649946 | 0.82 | TERT (1.00) | TERTMAPTHPGDKDM4ECYP19A1 | |
| SCHEMBL6804531 | 0.81 | TERT (0.81) | TERTMAPTHPGDKDM4ECYP19A1 | |
| SCHEMBL6615955 | 0.81 | TERT (0.74) | TERTMAPTHPGDKDM4ECYP19A1 | |
| SCHEMBL31632435 | 0.80 | CYP19A1 (0.74) | TERTMAPTHPGDKDM4ECYP19A1 | |
| SCHEMBL6618127 | 0.80 | TERT (0.78) | TERTMAPTHPGDKDM4ECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240016766-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF INNER EAR DISORDERS THROUGH LOCAL ADMINISTRATION IN THE TYMPANIC AREA | AB SCIENCE (FR) | 2024-01-18 | — | — | US | disclosed |
| EP-4251127-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF INNER EAR DISORDERS THROUGH LOCAL ADMINISTRATION IN THE TYMPANIC AREA | Moussy, Alain (FR) | 2023-10-04 | — | — | EP | disclosed |
| WO-2022112511-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF INNER EAR DISORDERS THROUGH LOCAL ADMINISTRATION IN THE TYMPANIC AREA | MOUSSY ALAIN (FR) | 2022-06-02 | — | — | WO | disclosed |