Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 10/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | HPGD | P15428 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 3/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 3/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.76 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.76 |
| ▸ | IKBKB | O14920 | 1/20 | 0.76 |
| ▸ | MAOA | P21397 | 1/20 | 0.76 |
| ▸ | MAOB | P27338 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 7,8-Dihydroxyflavone SCHEMBL29374601 | 0.87 | TERT (1.00) | TERTCYP3A4ALDH1A1HPGDMAPT | |
| 7,8-Dihydroxyflavone SCHEMBL419316 | 0.87 | TERT (1.00) | TERTCYP3A4ALDH1A1HPGDMAPT | |
| SCHEMBL7378162 | 0.86 | CYP3A4 (0.76) | TERTCYP3A4ALDH1A1HPGDMAPT | |
| SCHEMBL6613777 | 0.86 | TERT (0.76) | TERTCYP3A4ALDH1A1HPGDMAPT | |
| SCHEMBL6617302 | 0.86 | TERT (0.76) | TERTCYP3A4ALDH1A1HPGDMAPT | |
| 7,8-Dihydroxyflavone SCHEMBL21852713 | 0.85 | TERT (0.97) | TERTCYP3A4ALDH1A1HPGDMAPT | |
| SCHEMBL4649959 | 0.84 | TERT (1.00) | TERTCYP3A4ALDH1A1HPGDMAPT | |
| SCHEMBL31322174 | 0.84 | TERT (1.00) | TERTCYP3A4ALDH1A1HPGDMAPT | |
| SCHEMBL35318 | 0.84 | TERT (1.00) | TERTCYP3A4ALDH1A1HPGDMAPT | |
| SCHEMBL8514810 | 0.83 | TERT (0.70) | TERTCYP3A4ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122029177-A | Oligonucleotides containing multiple ligands and/or lipids | 阿达尔克斯制药有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122028913-A | Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions | 阿达尔克斯制药有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122029176-A | Containing a plurality of oligonucleotides modified oligonucleotides | 阿达尔克斯制药有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-20250161459-A1 | TRKB LIGAND CONJUGATED COMPOUNDS AND USES THEREOF | ADARX PHARMACEUTICALS, INC. (US) | 2025-05-22 | — | — | US | claimed |
| WO-2025038960-A1 | OLIGONUCLEOTIDES CONTAINING A LIGAND AT AN INTERNAL POSITION | ADARX PHARMACEUTICALS, INC. (US) | 2025-02-20 | — | — | WO | claimed |
| WO-2025038963-A1 | OLIGONUCLEOTIDES CONTAINING MULTIPLE LIGANDS AND/OR LIPIDS | ADARX PHARMACEUTICALS, INC. (US) | 2025-02-20 | — | — | WO | claimed |
| WO-2025038970-A1 | MODIFIED OLIGONUCLEOTIDES CONTAINING MULTIPLE OLIGONUCLEOTIDES | ADARX PHARMACEUTICALS, INC. (US) | 2025-02-20 | — | — | WO | claimed |
| EP-4475837-A2 | TRKB LIGAND CONJUGATED COMPOUNDS AND USES THEREOF | Adarx Pharmaceuticals, Inc. (US) | 2024-12-18 | — | — | EP | claimed |
| CN-118973616-A | Trkb ligand conjugated compounds and uses thereof | 阿达尔克斯制药有限公司 | 2024-11-15 | — | — | CN | claimed |
| WO-2023154896-A2 | TRKB LIGAND CONJUGATED COMPOUNDS AND USES THEREOF | ADARX PHARMACEUTICALS, INC. (US) | 2023-08-17 | — | — | WO | claimed |
| US-20220031641-A1 | COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING COGNITIVE DYSFUNCTION | PHARMATROPHIX, INC. | 2022-02-03 | — | — | US | claimed |
| US-20210244768-A1 | CELL COMPOSITIONS AND USES THEREOF | THE UNIVERSITY OF SYDNEY (AU) | 2021-08-12 | — | — | US | claimed |
| US-20190022101-A1 | Treating Cochlear Synaptopathy | MASSACHUSETTS EYE AND EAR INFIRMARY (US) | 2019-01-24 | — | — | US | claimed |
| WO-2017120465-A1 | TREATING COCHLEAR SYNAPTOPATHY | MASSACHUSETTS EYE AND EAR INFIRMARY (US) | 2017-07-13 | — | — | WO | claimed |
| WO-2016112012-A1 | TRKB AGONISTS AS NOVEL TREATMENT FOR ACUTE AND CHRONIC CARDIAC DISEASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-07-14 | — | — | WO | claimed |
| US-20130040947-A1 | TRKB AGONISTS AND METHODS OF USE | EMORY UNIVERSITY (US) | 2013-02-14 | — | — | US | claimed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130040947-A1 | TRKB AGONISTS AND METHODS OF USE | NTRK2, BDNF, NTRK1 | TERT 2930/4885CYP3A4 1228/4885ALDH1A1 1116/4885 |
| US-20220031641-A1 | COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING COGNITIVE DYSFUNCTION | CHRM3, CHAT, CHRM5 | TERT 2814/4885CYP3A4 2633/4885ALDH1A1 2748/4885 |
| US-20250161459-A1 | TRKB LIGAND CONJUGATED COMPOUNDS AND USES THEREOF | NTRK2, NTRK1, BDNF | TERT 2994/4885CYP3A4 4808/4885ALDH1A1 1653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.