Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 9/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2937599 | 1.00 | SLC6A9 (0.50) | SLC6A9NOTUMHSD11B1AOC3GPR55 | |
| SCHEMBL2940287 | 0.89 | SLC6A9 (0.47) | SLC6A9NOTUMAOC3GPR55KCNH2 | |
| SCHEMBL2940289 | 0.89 | SLC6A9 (0.47) | SLC6A9NOTUMAOC3GPR55KCNH2 | |
| SCHEMBL2939305 | 0.89 | NOTUM (0.60) | SLC6A9NOTUMHSD11B1 | |
| SCHEMBL2939303 | 0.89 | NOTUM (0.60) | SLC6A9NOTUMHSD11B1 | |
| SCHEMBL13363551 | 0.85 | SLC6A9 (0.50) | SLC6A9NOTUMAOC3KCNH2GPR119 | |
| SCHEMBL2937751 | 0.82 | SLC6A9 (0.51) | SLC6A9HSD11B1GPR55KCNH2GPR119 | |
| SCHEMBL2937750 | 0.82 | SLC6A9 (0.51) | SLC6A9HSD11B1GPR55KCNH2GPR119 | |
| SCHEMBL2939585 | 0.80 | SLC6A9 (0.48) | SLC6A9NOTUMKCNH2GPR119 | |
| SCHEMBL2939582 | 0.80 | SLC6A9 (0.48) | SLC6A9NOTUMKCNH2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134704-B1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2010-09-22 | — | — | EP | disclosed |
| US-20100120807-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2010-05-13 | — | — | US | disclosed |
| EP-2134704-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008109702-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2008-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120807-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | GPR119, GPR65, GPR39 | SLC6A9 2063/4885NOTUM 4356/4885HSD11B1 1559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.