SCHEMBL5854489

SCHEMBL5854489

Cc1cccc2nc3ccccc3cc12.OBO

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.53
HPGD P15428 4/20 0.53
KDM4E B2RXH2 3/20 0.53
GLA P06280 2/20 0.53
GAA P10253 2/20 0.53
NPC1 O15118 1/20 0.53
LMNA P02545 1/20 0.53
POLB P06746 1/20 0.53
PTBP1 P26599 1/20 0.53
RAB9A P51151 1/20 0.53
KMT2A Q03164 1/20 0.53
RCE1 Q9Y256 1/20 0.53
MAPT P10636 2/20 0.48
ACHE P22303 1/20 0.48
PDE10A Q9Y233 1/20 0.47
TDP1 Q9NUW8 1/20 0.46
STAT3 P40763 1/20 0.46
CYP2A6 P11509 2/20 0.45
NQO2 P16083 1/20 0.44
CYP1A2 P05177 5/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29376451 0.93 ALDH1A1 (0.60) ALDH1A1HPGDKDM4EGLAGAA
SCHEMBL291182 0.93 ALDH1A1 (0.60) ALDH1A1HPGDKDM4EGLAGAA
Hydrochloric Acid SCHEMBL28881738 0.91 ALDH1A1 (0.58) ALDH1A1HPGDKDM4EGLAGAA
Nitric Acid SCHEMBL27968557 0.83 KMT2A (0.49) ALDH1A1HPGDKDM4EGLAGAA
Nitric Acid SCHEMBL3961222 0.83 KMT2A (0.49) ALDH1A1HPGDKDM4EGLAGAA
SCHEMBL27873813 0.81 ALDH1A1 (0.49) ALDH1A1HPGDKDM4EGLAGAA
SCHEMBL38662128 0.81 TSHR (0.47) ALDH1A1HPGDKDM4EGLAGAA
SCHEMBL28146547 0.81 ALDH1A1 (0.45) ALDH1A1HPGDKDM4EGLAGAA
Trifluoromethanesulfonic Acid SCHEMBL3855068 0.80 ALDH1A1 (0.44) ALDH1A1HPGDKDM4EGLAGAA
SCHEMBL28229302 0.79 ALDH1A1 (0.53) ALDH1A1HPGDKDM4EGLAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7045361-B2 Analyte sensing via acridine-based boronate biosensors MEDTRONIC MINIMED, INC. (US) 2006-05-16 US disclosed
US-20050191761-A1 ANALYTE SENSING VIA ACRIDINE-BASED BORONATE BIOSENSORS MEDTRONIC MINIMED INC. 2005-09-01 US disclosed