Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 12/20 | 1.00 |
| ▸ | ROCK1 | Q13464 | 11/20 | 1.00 |
| ▸ | PRKACA | P17612 | 5/20 | 1.00 |
| ▸ | PRKCD | Q05655 | 5/20 | 1.00 |
| ▸ | PRKD3 | O94806 | 4/20 | 1.00 |
| ▸ | PRKCZ | Q05513 | 4/20 | 1.00 |
| ▸ | PRKACG | P22612 | 4/20 | 1.00 |
| ▸ | PRKACB | P22694 | 4/20 | 1.00 |
| ▸ | PKN2 | Q16513 | 3/20 | 1.00 |
| ▸ | AURKB | Q96GD4 | 3/20 | 1.00 |
| ▸ | PRKD2 | Q9BZL6 | 3/20 | 1.00 |
| ▸ | PLK4 | O00444 | 2/20 | 1.00 |
| ▸ | MARK3 | P27448 | 2/20 | 1.00 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 1.00 |
| ▸ | MARK2 | Q7KZI7 | 2/20 | 1.00 |
| ▸ | MAP4K4 | O95819 | 2/20 | 1.00 |
| ▸ | CHEK2 | O96017 | 2/20 | 1.00 |
| ▸ | AKT1 | P31749 | 2/20 | 1.00 |
| ▸ | PRKX | P51817 | 2/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29372951 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PRKACAPRKCDPRKD3 | |
| SCHEMBL6969527 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PRKACAPRKCDPRKD3 | |
| SCHEMBL226317 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PRKACAPRKCDPRKD3 | |
| SCHEMBL30069136 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PRKACAPRKCDPRKD3 | |
| SCHEMBL124161 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PRKACAPRKCDPRKD3 | |
| SCHEMBL29677841 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PRKACAPRKCDPRKD3 | |
| Hydrochloric Acid SCHEMBL2456059 | 0.99 | ROCK2 (0.98) | ROCK2ROCK1PRKACAPRKCDPRKD3 | |
| Hydrochloric Acid SCHEMBL507871 | 0.99 | ROCK2 (0.98) | ROCK2ROCK1PRKACAPRKCDPRKD3 | |
| Hydrochloric Acid SCHEMBL2461354 | 0.99 | ROCK2 (0.98) | ROCK2ROCK1PRKACAPRKCDPRKD3 | |
| Hydrochloric Acid SCHEMBL29781011 | 0.99 | ROCK2 (0.98) | ROCK2ROCK1PRKACAPRKCDPRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3843845-B1 | INHIBITION OF PROTEIN KINASES TO TREAT FRIEDREICH ATAXIA | UNIV MASSACHUSETTS (US) | 2026-03-11 | — | — | EP | claimed |
| US-20250017977-A1 | HEPATOCYTES AND HEPATIC NON-PARENCHYMAL CELLS, AND METHODS FOR PREPARATION THEREOF | THE UNIVERSITY OF TOKYO (JP) | 2025-01-16 | — | — | US | claimed |
| WO-2024128696-A1 | METHOD FOR INDUCING DIFFERENTIATION OF STEM CELLS INTO CORNEAL ENDOTHELIAL CELLS AND USE THEREOF | 재단법인 아산사회복지재단 | 2024-06-20 | — | — | WO | claimed |
| US-20260009003-A1 | MANUFACTURING OF THERAPEUTIC SATELLITE CELLS FOR TREATING MUSCULAR DYSTROPHY | VITA THERAPEUTICS INC (US) | 2026-01-08 | — | — | US | disclosed |
| US-20250179428-A1 | METHOD FOR INDUCING DIFFERENTIATION OF CORNEAL EPITHELIAL CELLS FROM PLURIPOTENT STEM CELLS | OSAKA UNIVERSITY (JP) | 2025-06-05 | — | — | US | disclosed |
| US-12247219-B2 | Method for inducing differentiation of corneal epithelial cells from pluripotent stem cells | OSAKA UNIVERSITY (JP) | 2025-03-11 | — | — | US | disclosed |
| CN-119546748-A | Fibrin gel sheet for cell transplantation | 千纸鹤治疗公司 | 2025-02-28 | — | — | CN | disclosed |
| US-20250017977-A1 | HEPATOCYTES AND HEPATIC NON-PARENCHYMAL CELLS, AND METHODS FOR PREPARATION THEREOF | THE UNIVERSITY OF TOKYO (JP) | 2025-01-16 | — | — | US | disclosed |
| CN-119072542-A | Maturation-promoting agent having ALK 5-inhibiting activity and CDK 8/19-inhibiting activity | 千纸鹤治疗公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-112867787-B | Insulin producing cells | 千纸鹤治疗公司 | 2024-11-22 | — | — | CN | disclosed |
| US-20240376435-A1 | KIDNEY ORGANOID AND METHOD FOR PRODUCING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-11-14 | — | — | US | disclosed |
| CN-116829697-A | Ripening agent | 千纸鹤治疗公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116391028-A | Ripening agent | 千纸鹤治疗公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-116355850-A | Construction method and application of colorectal cancer organoids | 中国医学科学院基础医学研究所 | 2023-06-30 | — | — | CN | disclosed |
| WO-2023033137-A1 | KIDNEY ORGANOID AND METHOD FOR PRODUCING SAME | 大塚製薬株式会社 | 2023-03-09 | — | — | WO | disclosed |
| EP-3246394-B1 | METHOD FOR INDUCING DIFFERENTIATION OF CORNEAL EPITHELIAL CELLS FROM PLURIPOTENT STEM CELLS | UNIV OSAKA (JP) | 2022-11-23 | — | — | EP | disclosed |
| WO-2022107877-A1 | MATURATION AGENT | オリヅルセラピューティクス株式会社 | 2022-05-27 | — | — | WO | disclosed |
| EP-3990624-A1 | ENHANCED DIFFERENTIATION OF BETA CELLS | Vertex Pharmaceuticals Incorporated (US) | 2022-05-04 | — | — | EP | disclosed |
| US-20220041990-A1 | METHODS, COMPOSITIONS, AND KITS FOR PRODUCING SKELETAL MUSCLE STEM CELLS AND TREATING DISORDERS | UNIV JOHNS HOPKINS (US) | 2022-02-10 | — | — | US | disclosed |
| EP-3945827-A2 | METHODS, COMPOSITIONS, AND KITS FOR PRODUCING SKELETAL MUSCLE STEM CELLS AND TREATING DISORDERS | The Johns Hopkins University (US) | 2022-02-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220041990-A1 | METHODS, COMPOSITIONS, AND KITS FOR PRODUCING SKELETAL MUSCLE STEM CELLS AND TREATING DISORDERS | TNNC1, CKMT1A; CKMT1B, MYLK2 | ROCK2 2530/4885ROCK1 2099/4885PRKACA 1212/4885 |
| US-20260009003-A1 | MANUFACTURING OF THERAPEUTIC SATELLITE CELLS FOR TREATING MUSCULAR DYSTROPHY | CAPNS1, CAPN1, CAPN2 | ROCK2 3736/4885ROCK1 4110/4885PRKACA 3481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.