Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21356206 | 1.00 | DUT (0.32) | DUTMPO | |
| SCHEMBL21355872 | 0.86 | DUT (0.31) | DUT | |
| SCHEMBL17398622 | 0.78 | DUT (0.32) | DUT | |
| SCHEMBL20160917 | 0.77 | GPR84 (0.35) | DUT | |
| SCHEMBL23409589 | 0.76 | — | — | |
| SCHEMBL31691600 | 0.74 | KDM4E (0.34) | DUT | |
| SCHEMBL26772128 | 0.74 | APLNR (0.33) | — | |
| SCHEMBL9031600 | 0.74 | — | — | |
| SCHEMBL19208399 | 0.71 | DUT (0.36) | DUTMPO | |
| SCHEMBL20898062 | 0.71 | CA12 (0.34) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3765461-B1 | SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5 (PRMT5) | PRELUDE THERAPEUTICS INC (US) | 2023-08-30 | — | — | EP | disclosed |
| EP-3946352-A1 | SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5 | Prelude Therapeutics, Incorporated (US) | 2022-02-09 | — | — | EP | disclosed |