Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3277622 | 0.82 | CA1 (0.57) | CTSDCA1CA2CA12CA4 | |
| SCHEMBL28558451 | 0.77 | RAB9A (0.54) | CTSDCA1CA2CA12CA4 | |
| SCHEMBL261633 | 0.75 | MEN1 (0.31) | MAPTHSD17B10HTT | |
| SCHEMBL28708068 | 0.73 | GAA (0.51) | TSHRTP53GAAMAPTMAPK1 | |
| SCHEMBL8363515 | 0.72 | CTSD (0.54) | CTSDCA1CA2CA12CA4 | |
| SCHEMBL22926249 | 0.72 | CA1 (0.56) | CTSDCA1CA2CA12CA4 | |
| SCHEMBL10606932 | 0.72 | ALDH1A1 (0.57) | CTSDCA1CA2CA12CA4 | |
| SCHEMBL157181 | 0.71 | CA1 (0.60) | CTSDCA1CA2CA12CA4 | |
| SCHEMBL27882858 | 0.71 | CTSD (0.45) | CTSDCA1CA2CA12CA4 | |
| SCHEMBL610415 | 0.70 | MEN1 (0.41) | CA1CA2CA12CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1978967-B1 | QUINAZOLINONE DERIVATIVES AS VANILLOID ANTAGONISTS | NOVARTIS AG (CH) | 2010-09-22 | — | — | EP | claimed |