SCHEMBL29387474

SCHEMBL29387474

CCCCCn1c(C)c(C(=O)c2cccc3ccc(C)cc23)c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 20/20 1.00
CNR1 P21554 11/20 0.83
SLC6A3 Q01959 1/20 0.83
MEN1 O00255 1/20 0.70
NR1I2 O75469 1/20 0.70
ALDH1A1 P00352 1/20 0.70
CYP1A2 P05177 1/20 0.70
MAPT P10636 1/20 0.70
HPGD P15428 1/20 0.70
TSHR P16473 1/20 0.70
MAPK1 P28482 1/20 0.70
CYP2C19 P33261 1/20 0.70
KMT2A Q03164 1/20 0.70
NR1H4 Q96RI1 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6323198 1.00 CNR2 (1.00) CNR2CNR1SLC6A3MEN1NR1I2
SCHEMBL29385330 0.97 CNR2 (0.94) CNR2CNR1SLC6A3MEN1NR1I2
SCHEMBL6324281 0.92 CNR2 (1.00) CNR2CNR1SLC6A3MEN1NR1I2
SCHEMBL29989324 0.92 CNR2 (1.00) CNR2CNR1SLC6A3MEN1NR1I2
SCHEMBL16344141 0.91 CNR2 (1.00) CNR2CNR1SLC6A3MEN1NR1I2
SCHEMBL29362163 0.91 CNR2 (1.00) CNR2CNR1SLC6A3MEN1NR1I2
SCHEMBL29988980 0.90 CNR2 (1.00) CNR2CNR1SLC6A3MEN1NR1I2
SCHEMBL6325869 0.90 CNR2 (1.00) CNR2CNR1SLC6A3MEN1NR1I2
SCHEMBL29988870 0.88 CNR2 (1.00) CNR2CNR1SLC6A3MEN1NR1I2
SCHEMBL6325579 0.88 CNR2 (1.00) CNR2CNR1SLC6A3MEN1NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260076921-A1 Transdermal Pharmaceutical Formulations for the Treatment of Multiple Sclerosis PIKE THERAPEUTICS INC (CA) 2026-03-19 US disclosed
US-20250312359-A1 Transdermal Delivery of Tetrahydrocannabinol Pike Therapeutics Inc. (CA) 2025-10-09 US disclosed
US-20250275935-A1 COMPOSITIONS AND METHODS FOR TREATING PATIENTS WITH DEMENTIA DUE TO ALZHEIMER'S DISEASE WITH A COMBINATION OF THC AND MELATONIN IGC PHARMA IP, LLC (US) 2025-09-04 US disclosed
US-20250248948-A1 Transdermal and/or Topical, Pharmaceutical Formulations Comprising Cannabidiol and/or Tetrahydrocannabinol for the Treatment of Chronic Pain PIKE THERAPEUTICS INC (CA) 2025-08-07 US disclosed
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES Ananda Scientific, Inc. (US) 2025-06-19 US disclosed
US-20250186363-A1 Pharmaceutical Compositions and Methods for Treating Parkinson's Disease PIKE THERAPEUTICS INC (CA) 2025-06-12 US disclosed
EP-4558135-A1 CONTINUOUS DELIVERY SYSTEMS COMPRISING A CANNABINOID AND MEDICINAL USES THEREOF Pike Therapeutics Inc. (CA) 2025-05-28 EP disclosed
CN-119923256-A Continuous delivery system comprising cannabinoids and medical uses thereof 长矛治疗股份有限公司 2025-05-02 CN disclosed
US-12268699-B2 Transdermal delivery of tetrahydrocannabinol Pike Therapeutics Inc. (CA) 2025-04-08 US disclosed
US-20250009768-A1 Transdermal Delivery of Tetrahydrocannabinol Pike Therapeutics Inc. (CA) 2025-01-09 US disclosed
WO-2022224184-A1 TRANSDERMAL PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT OF CHRONIC PAIN PIKE THERAPEUTICS, INC. (CA) 2022-10-27 WO disclosed
WO-2022219468-A1 TRANSDERMAL DELIVERY OF CANNABIDIOL PIKE THERAPEUTICS, INC. 1219014 B.C. LTD. (CA) 2022-10-20 WO disclosed
WO-2022217147-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES ROSENFELD MARK J (US) 2022-10-13 WO disclosed
EP-4045024-A1 TRANSDERMAL DELIVERY OF CANNABIDIOL Pike Therapeutics, Inc., 1219014 B.C. Ltd. (CA) 2022-08-24 EP disclosed
US-20220175718-A1 TRANSDERMAL PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT OF CANCER PIKE THERAPEUTICS INC (CA) 2022-06-09 US disclosed
WO-2022118303-A1 TRANSDERMAL PHARMACEUTICAL FORMULATIONS COMPRISING CBD OR THC FOR THE TREATMENT OF CANCER PIKE THERAPEUTICS, INC. (CA) 2022-06-09 WO disclosed
CN-114555068-A Transdermal administration of cannabidiol 长矛治疗股份有限公司1219014 B.C.有限公司 2022-05-27 CN disclosed
WO-2022038475-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING PARKINSON'S DISEASE PIKE THERAPEUTICS, INC. (CA) 2022-02-24 WO disclosed
US-20220047541-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING PARKINSON'S DISEASE Pike Therapeutics Inc. (CA) 2022-02-17 US disclosed
US-20220047525-A1 TRANSDERMAL PHARMACEUTICAL FORMULATIONS OF NABILONE ALONE AND IN COMBINATION WITH CANNABINOIDS PIKE THERAPEUTICS INC (CA) 2022-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250248948-A1 Transdermal and/or Topical, Pharmaceutical Formulations Comprising Cannabidiol and/or Tetrahydrocannabinol for the Treatment of Chronic Pain CNR2, CNR1, TRPV1 CNR2 1/4885CNR1 2/4885SLC6A3 1390/4885
US-20260076921-A1 Transdermal Pharmaceutical Formulations for the Treatment of Multiple Sclerosis SOST, CNR2, BHMT2 CNR2 2/4885CNR1 25/4885SLC6A3 1828/4885
US-20220175718-A1 TRANSDERMAL PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT OF CANCER CNR2, CNR1, DSG1 CNR2 1/4885CNR1 2/4885SLC6A3 1030/4885
US-20250186363-A1 Pharmaceutical Compositions and Methods for Treating Parkinson's Disease PARK7, SNCA, COMT CNR2 422/4885CNR1 613/4885SLC6A3 60/4885
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES CNR2, CNR1, FAAH CNR2 1/4885CNR1 2/4885SLC6A3 1646/4885
US-20220047541-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING PARKINSON'S DISEASE PARK7, SNCA, COMT CNR2 422/4885CNR1 613/4885SLC6A3 60/4885
US-20250312359-A1 Transdermal Delivery of Tetrahydrocannabinol CNR2, CNR1, OPRL1 CNR2 1/4885CNR1 2/4885SLC6A3 861/4885
US-12268699-B2 Transdermal delivery of tetrahydrocannabinol CNR2, CNR1, OPRL1 CNR2 1/4885CNR1 2/4885SLC6A3 861/4885
US-20220047525-A1 TRANSDERMAL PHARMACEUTICAL FORMULATIONS OF NABILONE ALONE AND IN COMBINATION WITH CANNABINOIDS CNR2, CNR1, FAAH CNR2 1/4885CNR1 2/4885SLC6A3 392/4885
US-20250009768-A1 Transdermal Delivery of Tetrahydrocannabinol CNR2, CNR1, OPRL1 CNR2 1/4885CNR1 2/4885SLC6A3 861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.