Metazocine

Metazocine

SCHEMBL29387774

C[C@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 8/20 1.00
OPRD1 P41143 7/20 1.00
OPRK1 P41145 7/20 1.00
SIGMAR1 Q99720 7/20 1.00
MRGPRX2 Q96LB1 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metazocine SCHEMBL13353229 1.00 OPRM1 (1.00) OPRM1OPRD1OPRK1SIGMAR1MRGPRX2
Metazocine SCHEMBL21994208 1.00 OPRM1 (1.00) OPRM1OPRD1OPRK1SIGMAR1MRGPRX2
Metazocine SCHEMBL12013732 1.00 OPRM1 (1.00) OPRM1OPRD1OPRK1SIGMAR1MRGPRX2
Metazocine SCHEMBL1649365 1.00 OPRM1 (1.00) OPRM1OPRD1OPRK1SIGMAR1MRGPRX2
Metazocine SCHEMBL12049577 1.00 OPRM1 (1.00) OPRM1OPRD1OPRK1SIGMAR1MRGPRX2
Metazocine SCHEMBL26347 1.00 OPRM1 (1.00) OPRM1OPRD1OPRK1SIGMAR1MRGPRX2
SCHEMBL15866689 0.92 SIGMAR1 (0.85) OPRM1OPRD1OPRK1SIGMAR1MRGPRX2
SCHEMBL12267534 0.84 SIGMAR1 (0.73) OPRM1OPRD1OPRK1SIGMAR1MRGPRX2
SCHEMBL12324824 0.84 SIGMAR1 (0.73) OPRM1OPRD1OPRK1SIGMAR1MRGPRX2
SCHEMBL12716235 0.84 SIGMAR1 (0.73) OPRM1OPRD1OPRK1SIGMAR1MRGPRX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3064199-B1 ABUSE-DETERRENT TRANSDERMAL FORMULATIONS OF OPIATE AGONISTS AND AGONIST-ANTAGONISTS BUZZZ PHARMACEUTICALS LTD (IE) 2023-12-20 EP claimed
EP-3313407-B1 TREATMENT AND MANAGEMENT OF AUGMENTATION IN RESTLESS LEGS SYNDROME UNIV EAST CAROLINA (US) 2023-07-19 EP claimed
EP-3385252-B1 CANNABINOID RECEPTOR MODULATORS ARENA PHARM INC (US) 2022-09-21 EP claimed
EP-3291676-B1 MITRAGYNINE ANALOGS AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-08-17 EP claimed
CN-119818470-A Pharmaceutical composition containing melagatran besylate and preparation method thereof 齐鲁制药(海南)有限公司 2025-04-15 CN disclosed
EP-1765303-B2 ORAL TABLET SAFEGUARDED AGAINST ABUSE GRUENENTHAL GMBH (DE) 2022-11-23 EP disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed