Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 1.00 |
| ▸ | OPRD1 | P41143 | 7/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 7/20 | 1.00 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 1.00 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Metazocine SCHEMBL21994208 | 1.00 | OPRM1 (1.00) | OPRM1OPRD1OPRK1SIGMAR1MRGPRX2 | |
| Metazocine SCHEMBL12013732 | 1.00 | OPRM1 (1.00) | OPRM1OPRD1OPRK1SIGMAR1MRGPRX2 | |
| Metazocine SCHEMBL1649365 | 1.00 | OPRM1 (1.00) | OPRM1OPRD1OPRK1SIGMAR1MRGPRX2 | |
| Metazocine SCHEMBL12049577 | 1.00 | OPRM1 (1.00) | OPRM1OPRD1OPRK1SIGMAR1MRGPRX2 | |
| Metazocine SCHEMBL29387774 | 1.00 | OPRM1 (1.00) | OPRM1OPRD1OPRK1SIGMAR1MRGPRX2 | |
| Metazocine SCHEMBL26347 | 1.00 | OPRM1 (1.00) | OPRM1OPRD1OPRK1SIGMAR1MRGPRX2 | |
| SCHEMBL15866689 | 0.92 | SIGMAR1 (0.85) | OPRM1OPRD1OPRK1SIGMAR1MRGPRX2 | |
| SCHEMBL12267534 | 0.84 | SIGMAR1 (0.73) | OPRM1OPRD1OPRK1SIGMAR1MRGPRX2 | |
| SCHEMBL12324824 | 0.84 | SIGMAR1 (0.73) | OPRM1OPRD1OPRK1SIGMAR1MRGPRX2 | |
| SCHEMBL12716235 | 0.84 | SIGMAR1 (0.73) | OPRM1OPRD1OPRK1SIGMAR1MRGPRX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130512-A1 | FUSED-RING HETEROCYCLE OPIOIDS | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130512-A1 | FUSED-RING HETEROCYCLE OPIOIDS | OPRK1, OPRD1, OPRL1 | OPRM1 4/4885OPRD1 2/4885OPRK1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.