SCHEMBL29387992

SCHEMBL29387992

C[N+]1=C2C(=O)N=C(N)N=C2N([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.40
▸ SMN1; SMN2 Q16637 4/20 0.40
▸ ALDH1A1 P00352 3/20 0.40
▸ MTOR P42345 2/20 0.40
▸ TP53 P04637 2/20 0.40
▸ HTT P42858 2/20 0.40
▸ BLM P54132 2/20 0.40
▸ THRB P10828 1/20 0.40
▸ MDM2 Q00987 1/20 0.40
▸ NCOA1 Q15788 1/20 0.40
▸ NCOA3 Q9Y6Q9 1/20 0.40
▸ POLB P06746 1/20 0.40
▸ GMNN O75496 1/20 0.40
▸ NFKB1 P19838 1/20 0.40
▸ DNMT1 P26358 1/20 0.40
▸ THPO P40225 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ HBB P68871 1/20 0.40
▸ PMP22 Q01453 1/20 0.40
▸ MAPT P10636 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31529987 0.88 LMNA (0.39) LMNASMN1; SMN2ALDH1A1MTORTP53
SCHEMBL29424715 0.82 MEN1 (0.38) LMNASMN1; SMN2ALDH1A1MTORTP53
SCHEMBL114650 0.76 LMNA (0.45) LMNASMN1; SMN2ALDH1A1MTORTP53
SCHEMBL9147640 0.75 LMNA (0.44) LMNASMN1; SMN2ALDH1A1MTORTP53
SCHEMBL9343755 0.74 LMNA (0.44) LMNASMN1; SMN2ALDH1A1MTORTP53
Phosphoric Acid SCHEMBL6465085 0.73 LMNA (0.42) LMNASMN1; SMN2ALDH1A1MTORTP53
Phosphoric Acid SCHEMBL20305093 0.73 LMNA (0.42) LMNASMN1; SMN2ALDH1A1MTORTP53
SCHEMBL31685308 0.67 LMNA (0.36) LMNASMN1; SMN2ALDH1A1MTORTP53
SCHEMBL30612476 0.67 EGFR (0.39) LMNASMN1; SMN2ALDH1A1MTORTP53
SCHEMBL31685392 0.64 LMNA (0.43) LMNASMN1; SMN2ALDH1A1MTORTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705481-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2026-03-11 — — EP claimed
EP-4634380-A1 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION ModernaTX, Inc. (US) 2025-10-22 — — EP claimed
WO-2025151711-A1 NUCLEIC ACID VACCINES TARGETING METHANOGENS Arkea Bio Corp. (US) 2025-07-17 — — WO claimed
EP-4554616-A1 COMPOSITIONS AND METHODS FOR REDUCING METHANE EMISSIONS IN RUMINANT POPULATIONS Arkea Bio Corp. (US) 2025-05-21 — — EP claimed
EP-4008334-B1 MANNOSE-BASED MRNA TARGETED DELIVERY SYSTEM AND USE THEREOF SHENZHEN RHEGEN BIOTECHNOLOGY CO LTD (CN) 2024-12-04 — — EP claimed
WO-2024233308-A2 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. (US) 2024-11-14 — — WO claimed
WO-2024129779-A1 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION MODERNATX, INC. (US) 2024-06-20 — — WO claimed
WO-2024015366-A1 COMPOSITIONS AND METHODS FOR REDUCING METHANE EMISSIONS IN RUMINANT POPULATIONS Arkea Bio Corp. (US) 2024-01-18 — — WO claimed
WO-2023178182-A1 COMPOSITIONS AND METHODS FOR DETECTION AND TREATMENT OF CORONAVIRUS INFECTION 10X GENOMICS, INC. (US) 2023-09-21 — — WO claimed
EP-4747380-A1 MODULATING EXPRESSION OF ALAS1 (5'-AMINOLEVULINATE SYNTHASE 1) GENE CRISPR Therapeutics AG (CH) 2026-05-27 — — EP disclosed
EP-4743437-A1 DIESTER LIPIDS, LIPID NANOPARTICLE CONTAINING DIESTER LIPIDS, AND FORMULATIONS THEREOF Providence Therapeutics Holdings Inc. (CA) 2026-05-20 — — EP disclosed
US-20260109976-A1 SYNTHETIC ENGINEERED RNA MOLECULES AND RELATED METHODS RNAV8 BIO INC (US) 2026-04-23 — — US disclosed
EP-4728063-A1 METHODS OF SIMULTANEOUSLY IDENTIFYING OR QUANTIFYING CAPPING AND TAILING MODIFICATIONS OF MESSENGER RNA Sanofi Pasteur Inc. (US) 2026-04-22 — — EP disclosed
EP-4709417-A2 POLYNUCLEOTIDES ENCODING NOROVIRUS VP1 ANTIGENS AND USES THEREOF Merck Sharp & Dohme LLC (US) 2026-03-18 — — EP disclosed
EP-3983545-A1 COMPOSITIONS AND METHODS FOR EDITING BETA-GLOBIN FOR TREATMENT OF HEMAGLOBINOPATHIES Vertex Pharmaceuticals Incorporated (US) 2022-04-20 — — EP disclosed
EP-3976057-A1 EXPANDED T CELL ASSAY ModernaTX, Inc. (US) 2022-04-06 — — EP disclosed
WO-2022066757-A1 IMPROVED METHODS AND COMPOSITIONS FOR EXPRESSION OF NUCLEIC ACIDS IN CELLS MYELOID THERAPEUTICS, INC. (US) 2022-03-31 — — WO disclosed
EP-3966327-A1 CRISPR/CAS ALL-IN-TWO VECTOR SYSTEMS FOR TREATMENT OF DMD Vertex Pharmaceuticals Incorporated (US) 2022-03-16 — — EP disclosed
EP-3958893-A1 MRNA FORMULATION eTheRNA Immunotherapies NV (BE) 2022-03-02 — — EP disclosed
WO-2022032154-A2 COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM MODERNATX, INC. (US) 2022-02-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109976-A1 SYNTHETIC ENGINEERED RNA MOLECULES AND RELATED METHODS UPF1, RNGTT, NSUN3 LMNA 1947/4885SMN1; SMN2 1804/4885ALDH1A1 4086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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