Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 7/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5152764 | 0.90 | GPR119 (0.44) | GPR119RORCABCB1 | |
| SCHEMBL310810 | 0.89 | GPR119 (0.37) | GPR119PDE5ARORCDDB1CRBN | |
| SCHEMBL1104538 | 0.89 | GPR119 (0.37) | GPR119PDE5ARORCDDB1CRBN | |
| SCHEMBL484203 | 0.84 | YAP1 (0.45) | — | |
| SCHEMBL483557 | 0.84 | YAP1 (0.45) | — | |
| SCHEMBL483558 | 0.84 | YAP1 (0.45) | — | |
| SCHEMBL483518 | 0.84 | YAP1 (0.45) | — | |
| Ethane SCHEMBL483694 | 0.84 | YAP1 (0.45) | — | |
| SCHEMBL31479820 | 0.81 | RIPK1 (0.47) | GPR119PDE5A | |
| SCHEMBL28285321 | 0.81 | GPR119 (0.43) | GPR119RORCABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114222728-A | Process for preparing alpha-carboxamide pyrrolidine derivatives | 生物基因公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-114026066-A | Process for preparing alpha-carboxamide pyrrolidine derivatives | 生物基因麻省公司 | 2022-02-08 | — | — | CN | disclosed |