Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5152764 | 0.87 | GPR119 (0.44) | RIPK1NR1H2RXRANR1H3GPR119 | |
| SCHEMBL483409 | 0.81 | KCNH2 (0.46) | MAOB | |
| SCHEMBL29388249 | 0.81 | GPR119 (0.38) | PDE5AGPR119 | |
| SCHEMBL28515805 | 0.80 | CALCRL (0.47) | RIPK1PDE5AGPR119PSEN1PSEN2 | |
| SCHEMBL28529951 | 0.79 | RIPK1 (0.44) | RIPK1PDE5AMAOBGPR119PSEN1 | |
| SCHEMBL28285321 | 0.78 | GPR119 (0.43) | RIPK1NR1H2RXRANR1H3GPR119 | |
| SCHEMBL20835546 | 0.77 | RIPK1 (0.42) | RIPK1PDE5AGPR119PSEN1PSEN2 | |
| SCHEMBL28515213 | 0.77 | PKM (0.41) | RIPK1PDE5AMAOBMAOANR1H2 | |
| SCHEMBL31479247 | 0.76 | RIPK1 (0.50) | RIPK1PDE5AMAOBMAOAGPR119 | |
| SCHEMBL21093668 | 0.76 | RIPK1 (0.50) | RIPK1PDE5AMAOBMAOAGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |