Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315721 | 0.88 | CA2 (0.41) | CA2CA9CA1 | |
| SCHEMBL1118549 | 0.86 | CA2 (0.39) | CA2CA9CA1 | |
| SCHEMBL2678685 | 0.84 | LPAR3 (0.42) | CA2CA9CA1 | |
| SCHEMBL17728705 | 0.84 | LPAR3 (0.42) | CA2CA9CA1 | |
| SCHEMBL1118545 | 0.84 | LPAR3 (0.42) | CA2CA9CA1 | |
| SCHEMBL37730 | 0.82 | CA2 (0.37) | CA2CA9CA1 | |
| SCHEMBL30865709 | 0.80 | CA2 (0.35) | CA2CA9CA1 | |
| SCHEMBL27540621 | 0.80 | CA2 (0.35) | CA2CA9CA1 | |
| SCHEMBL31375314 | 0.80 | CA2 (0.35) | CA2CA9CA1 | |
| SCHEMBL27810105 | 0.80 | CA2 (0.35) | CA2CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3655408-B1 | CONFORMATIONAL RESTRICTION OF CYANINE FLUOROPHORES IN FAR-RED AND NEAR-IR RANGE | US HEALTH (US) | 2021-07-14 | — | — | EP | claimed |
| US-10994029-B2 | Conformational restriction of cyanine fluorophores in far-red and near-IR range | THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2021-05-04 | — | — | US | claimed |
| US-20200179536-A1 | CONFORMATIONAL RESTRICTION OF CYANINE FLUOROPHORES IN FAR-RED AND NEAR-IR RANGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) | 2020-06-11 | — | — | US | claimed |
| EP-3655408-A1 | CONFORMATIONAL RESTRICTION OF CYANINE FLUOROPHORES IN FAR-RED AND NEAR-IR RANGE | The U.S.A. As Represented By The Secretary, Department Of Health And Human Services (US) | 2020-05-27 | — | — | EP | claimed |
| WO-2019040825-A1 | CONFORMATIONAL RESTRICTION OF CYANINE FLUOROPHORES IN FAR-RED AND NEAR-IR RANGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2019-02-28 | — | — | WO | claimed |
| US-11707537-B2 | Conformational restriction of cyanine fluorophores in far-red and near-IR range | THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2023-07-25 | — | — | US | disclosed |
| US-11707537-B2 | Conformational restriction of cyanine fluorophores in far-red and near-IR range | THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2023-07-25 | — | — | US | disclosed |
| US-20210220490-A1 | CONFORMATIONAL RESTRICTION OF CYANINE FLUOROPHORES IN FAR-RED AND NEAR-IR RANGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) | 2021-07-22 | — | — | US | disclosed |
| EP-3655408-B1 | CONFORMATIONAL RESTRICTION OF CYANINE FLUOROPHORES IN FAR-RED AND NEAR-IR RANGE | US HEALTH (US) | 2021-07-14 | — | — | EP | disclosed |
| US-10994029-B2 | Conformational restriction of cyanine fluorophores in far-red and near-IR range | THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2021-05-04 | — | — | US | disclosed |
| US-20200179536-A1 | CONFORMATIONAL RESTRICTION OF CYANINE FLUOROPHORES IN FAR-RED AND NEAR-IR RANGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) | 2020-06-11 | — | — | US | disclosed |
| EP-3655408-A1 | CONFORMATIONAL RESTRICTION OF CYANINE FLUOROPHORES IN FAR-RED AND NEAR-IR RANGE | The U.S.A. As Represented By The Secretary, Department Of Health And Human Services (US) | 2020-05-27 | — | — | EP | disclosed |
| EP-1019389-B1 | EPOTHILONE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2005-11-09 | — | — | EP | disclosed |
| EP-1531153-A1 | Epothilone derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-05-18 | — | — | EP | disclosed |
| EP-1526133-A1 | Epothilone derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-04-27 | — | — | EP | disclosed |
| EP-1493738-A1 | Epothilone derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-01-05 | — | — | EP | disclosed |
| US-20030220295-A1 | Microtubule-stabilizing agents useful in the treatment of a variety of cancers | R-PHARM US OPERATING LLC | 2003-11-27 | — | — | US | disclosed |
| US-6605599-B1 | Antiproliferation agents; exerting microtubule stabilizing effects | BRISTOL-MYERS SQUIBB COMPANY | 2003-08-12 | — | — | US | disclosed |
| EP-1019389-A2 | EPOTHILONE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999002514-A2 | EPOTHILONE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220295-A1 | Microtubule-stabilizing agents useful in the treatment of a variety of cancers | MAPRE1, TUBB3, MAPRE2 | CA2 3063/4885CA9 3078/4885CA1 2877/4885 |
| US-20210220490-A1 | CONFORMATIONAL RESTRICTION OF CYANINE FLUOROPHORES IN FAR-RED AND NEAR-IR RANGE | IK, FAR1, SPR | CA2 525/4885CA9 125/4885CA1 1012/4885 |
| US-10994029-B2 | Conformational restriction of cyanine fluorophores in far-red and near-IR range | IK, FAR1, SPR | CA2 525/4885CA9 125/4885CA1 1012/4885 |
| US-20200179536-A1 | CONFORMATIONAL RESTRICTION OF CYANINE FLUOROPHORES IN FAR-RED AND NEAR-IR RANGE | IK, FAR1, SPR | CA2 525/4885CA9 125/4885CA1 1012/4885 |
| US-11707537-B2 | Conformational restriction of cyanine fluorophores in far-red and near-IR range | IK, FAR1, SPR | CA2 525/4885CA9 125/4885CA1 1012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.