SCHEMBL29392602

SCHEMBL29392602

C[C@@H](O)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GRB2 P62993 1/20 0.66
▸ F2 P00734 1/20 0.56
▸ CAPN1 P07384 2/20 0.56
▸ NRP1 O14786 3/20 0.51
▸ NTSR1 P30989 7/20 0.50
▸ NTSR2 O95665 5/20 0.50
▸ BDKRB2 P30411 1/20 0.49
▸ APLNR P35414 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1247726 0.97 GRB2 (0.61) GRB2F2CAPN1NRP1NTSR1
SCHEMBL29362706 0.90 GRB2 (0.67) GRB2F2CAPN1NRP1NTSR1
SCHEMBL12237919 0.87 GRB2 (0.50) GRB2F2CAPN1NRP1NTSR1
SCHEMBL12899266 0.87 GRB2 (0.50) GRB2F2CAPN1NRP1NTSR1
SCHEMBL14227389 0.87 GRB2 (0.50) GRB2F2CAPN1NRP1NTSR1
SCHEMBL13084631 0.87 GRB2 (0.50) GRB2F2CAPN1NRP1NTSR1
SCHEMBL12261069 0.87 GRB2 (0.50) GRB2F2CAPN1NRP1NTSR1
SCHEMBL29364463 0.86 APLNR (0.55) GRB2F2CAPN1NRP1NTSR1
SCHEMBL29445609 0.85 F2 (0.57) GRB2F2NRP1NTSR1NTSR2
SCHEMBL1247795 0.83 OPRM1 (0.48) GRB2F2NRP1NTSR1NTSR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12290569-B2 Methods and compositions using peptides and proteins with c-terminal elements Sanford Burnham Prebys Medical Discovery Institute (US) 2025-05-06 — — US claimed
CN-114062564-B Detection method of taffeta and variants thereof 北京第一生物化学药业有限公司 2022-04-12 — — CN claimed
CN-114062564-A Detection method of taffeta and variants thereof 北京第一生物化学药业有限公司 2022-02-18 — — CN claimed
US-20260048133-A1 METHODS AND COMPOSITIONS USING PEPTIDES AND PROTEINS WITH C-TERMINAL ELEMENTS SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INST (US) 2026-02-19 — — US disclosed
US-12290569-B2 Methods and compositions using peptides and proteins with c-terminal elements Sanford Burnham Prebys Medical Discovery Institute (US) 2025-05-06 — — US disclosed
EP-2953978-B1 PHOSPHORYLCHOLINE CONJUGATES AND USES THEREOF TPCERA LTD (IL) 2024-10-23 — — EP disclosed
US-11795197-B2 Peptide compositions for immuno-oncology molecular imaging and targeted drug delivery CEDARS-SINAI MEDICAL CENTER (US) 2023-10-24 — — US disclosed
US-20230173097-A1 METHODS AND COMPOSITIONS RELATED TO PEPTIDES AND PROTEINS WITH C-TERMINAL ELEMENTS SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE 2023-06-08 — — US disclosed
EP-2250278-B1 METHODS AND COMPOSITIONS RELATED TO PEPTIDES AND PROTEINS WITH C-TERMINAL ELEMENTS BURNHAM INSTITUTE FOR MEDICAL RES (US) 2023-04-05 — — EP disclosed
US-11472844-B2 Peptidomimetics, method of synthesis and uses thereof CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2022-10-18 — — US disclosed
US-20220175941-A1 METHODS AND COMPOSITIONS USING PEPTIDES AND PROTEINS WITH C-TERMINAL ELEMENTS SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE 2022-06-09 — — US disclosed
EP-3724215-B1 PEPTIDOMIMETICS, METHOD OF SYNTHESIS AND USES THEREOF PASTEUR INSTITUT (FR) 2022-04-13 — — EP disclosed
CN-114062564-B Detection method of taffeta and variants thereof 北京第一生物化学药业有限公司 2022-04-12 — — CN disclosed
US-11260133-B2 Methods and compositions related to peptides and proteins with C-terminal elements SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) 2022-03-01 — — US disclosed
CN-114062564-A Detection method of taffeta and variants thereof 北京第一生物化学药业有限公司 2022-02-18 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11260133-B2 Methods and compositions related to peptides and proteins with C-terminal elements CD2BP2, CLTC, CLTA GRB2 264/4885F2 3960/4885CAPN1 444/4885
US-20260048133-A1 METHODS AND COMPOSITIONS USING PEPTIDES AND PROTEINS WITH C-TERMINAL ELEMENTS CMKLR2, CRKL, CMKLR1 GRB2 702/4885F2 4068/4885CAPN1 920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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