Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 6/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23165875 | 1.00 | PLA2G4A (0.45) | PLA2G4ANPC1MAOAMAOBHCAR3 | |
| SCHEMBL12670980 | 0.90 | PLA2G4A (0.45) | PLA2G4ANPC1HCAR3KMO | |
| SCHEMBL3644842 | 0.89 | NPC1 (0.54) | PLA2G4ANPC1MAOAMAOBKMO | |
| SCHEMBL29627172 | 0.89 | LMNA (0.39) | PLA2G4ANPC1KMOHDAC3HDAC1 | |
| SCHEMBL23165476 | 0.89 | LMNA (0.39) | PLA2G4ANPC1KMOHDAC3HDAC1 | |
| SCHEMBL29395869 | 0.88 | MAOA (0.44) | PLA2G4ANPC1MAOAMAOBKMO | |
| SCHEMBL24271183 | 0.88 | MAOA (0.44) | PLA2G4ANPC1MAOAMAOBKMO | |
| SCHEMBL29627173 | 0.86 | RAB9A (0.41) | NPC1MAOAMAOBDGAT1 | |
| SCHEMBL28753181 | 0.86 | RAB9A (0.41) | NPC1MAOAMAOBDGAT1 | |
| SCHEMBL17845097 | 0.85 | NPC1 (0.39) | PLA2G4ANPC1MAOAMAOBKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466844-B | N- (1H-imidazol-2-yl) benzamide compound and pharmaceutical composition comprising same as active ingredient | 康佳诺医疗科技发展有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-114466844-A | N- (1H-imidazol-2-yl) benzamide compounds and pharmaceutical compositions containing the same as active ingredient | 康佳诺医疗科技发展有限公司 | 2022-05-10 | — | — | CN | disclosed |
| WO-2022042666-A1 | SELECTIVE ROCK2 KINASE INHIBITOR | 杭州邦顺制药有限公司 | 2022-03-03 | — | — | WO | disclosed |