Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.34 |
| ▸ | CDC25B | P30305 | 6/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22569895 | 1.00 | PDE2A (0.42) | PDE2AHTR1AHTTKDM4ETSHR | |
| SCHEMBL18787319 | 0.86 | PDE2A (0.50) | PDE2AHTR1APTPN1CDC25BBCHE | |
| SCHEMBL24557909 | 0.85 | PDE2A (0.43) | PDE2AHTR1APTPN1CDC25BBCHE | |
| SCHEMBL29397234 | 0.85 | PDE2A (0.43) | PDE2AHTR1APTPN1CDC25BBCHE | |
| SCHEMBL13648975 | 0.82 | HTR1A (0.38) | PDE2AHTR1APTPN1CDC25BBCHE | |
| SCHEMBL22569957 | 0.79 | HTR1A (0.38) | PDE2AHTR1AKDM4ESRCBCHE | |
| SCHEMBL29398378 | 0.79 | HTR1A (0.38) | PDE2AHTR1AKDM4ESRCBCHE | |
| SCHEMBL22570013 | 0.79 | HTR1A (0.41) | PDE2AHTR1APTPN1CDC25BBCHE | |
| SCHEMBL22569897 | 0.78 | ADORA3 (0.49) | — | |
| SCHEMBL25379329 | 0.78 | PDE2A (0.44) | PDE2AHTR1APTPN1CDC25BBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3956341-A1 | CD73 INHIBITORS | Bioardis LLC (US) | 2022-02-23 | — | — | EP | disclosed |