Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.41 |
| ▸ | DRD4 | P21917 | 9/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29384773 | 0.80 | ERAP1 (0.45) | DRD2DRD4MAPTALDH1A1DRD3 | |
| SCHEMBL22499595 | 0.80 | ERAP1 (0.45) | DRD2DRD4MAPTALDH1A1DRD3 | |
| SCHEMBL29402230 | 0.72 | GSTO1 (0.45) | GAAMAPTALDH1A1 | |
| SCHEMBL29403481 | 0.72 | GSTO1 (0.45) | GAAMAPTALDH1A1 | |
| SCHEMBL29401680 | 0.72 | GSTO1 (0.46) | GAAMAPTALDH1A1 | |
| SCHEMBL29688026 | 0.66 | HTR1A (0.49) | DRD2DRD4GAAKDM4EHTR1A | |
| SCHEMBL23060175 | 0.65 | BID (0.40) | GAAMAPTALDH1A1 | |
| SCHEMBL7240468 | 0.65 | HTR7 (0.50) | DRD2DRD4MAPTALDH1A1HTR1A | |
| SCHEMBL10865646 | 0.65 | HTR1A (0.48) | DRD2DRD4GAAMAPTHTR1A | |
| SCHEMBL10865051 | 0.64 | DRD4 (0.48) | DRD2DRD4GAAMAPTHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174259-A | Modulators of intracellular chloride concentration | 意大利学院科技基金会 | 2022-03-11 | — | — | CN | claimed |
| CN-114174259-A | Modulators of intracellular chloride concentration | 意大利学院科技基金会 | 2022-03-11 | — | — | CN | disclosed |