SCHEMBL22499595

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29384773	1.00	ERAP1 (0.45)	ERAP1HRH1ALDH1A1CYP1A2CYP3A4
	Hydrochloric Acid SCHEMBL11714575	0.81	ALDH1A1 (0.45)	ERAP1ALDH1A1CYP1A2CYP3A4CYP2D6
	SCHEMBL11710337	0.80	ERAP1 (0.54)	ERAP1ALDH1A1CYP1A2CYP3A4CYP2D6
	SCHEMBL29399998	0.80	DRD2 (0.41)	ALDH1A1DRD2DRD4DRD3MAPT
	Hydrochloric Acid SCHEMBL11717209	0.79	ERAP1 (0.53)	ERAP1ALDH1A1CYP1A2CYP3A4CYP2D6
	Bromide SCHEMBL11706601	0.77	ALDH1A1 (0.53)	ALDH1A1CYP3A4CYP2C9CYP2C19SMN1; SMN2
	SCHEMBL11718138	0.77	ALDH1A1 (0.45)	ERAP1ALDH1A1CYP1A2CYP3A4CYP2D6
	Phenylpiperazine SCHEMBL11768963	0.72	GPR55 (0.46)	ERAP1ALDH1A1DRD3MAPT
	SCHEMBL22515474	0.72	HDAC3 (0.41)	ALDH1A1SMN1; SMN2MAPT
	SCHEMBL22499537	0.72	HDAC3 (0.41)	ALDH1A1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.