Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 6/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | MDM4 | O15151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30414754 | 0.92 | MDM2 (0.53) | MDM2TLR2MDM4TP53 | |
| SCHEMBL29400768 | 0.92 | MDM2 (0.53) | MDM2IDO1TLR2MDM4TP53 | |
| SCHEMBL14381107 | 0.92 | MDM2 (0.53) | MDM2IDO1TLR2MDM4TP53 | |
| SCHEMBL10131781 | 0.92 | MDM2 (0.53) | MDM2IDO1TLR2MDM4TP53 | |
| SCHEMBL117964 | 0.88 | MDM2 (0.55) | MDM2TLR2MDM4TP53 | |
| SCHEMBL29374829 | 0.88 | MDM2 (0.55) | MDM2TLR2MDM4TP53 | |
| SCHEMBL120511 | 0.88 | MDM2 (0.55) | MDM2TLR2MDM4TP53 | |
| SCHEMBL29792120 | 0.88 | MDM2 (0.55) | MDM2TLR2MDM4TP53 | |
| SCHEMBL29768913 | 0.88 | MDM2 (0.55) | MDM2TLR2MDM4TP53 | |
| SCHEMBL30649315 | 0.88 | MDM2 (0.55) | MDM2TLR2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12077561-B2 | CNP compounds | NOVO NORDISK A/S (DK) | 2024-09-03 | — | — | US | disclosed |
| US-20240209028-A1 | CNP COMPOUNDS | NOVO NORDISK A/S (DK) | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12077561-B2 | CNP compounds | NPPA, NPR1, NPR3 | MDM2 4172/4885IDO1 4501/4885TLR2 2326/4885 |
| US-20240209028-A1 | CNP COMPOUNDS | NPPA, NPR1, NPR3 | MDM2 4172/4885IDO1 4501/4885TLR2 2326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.