SCHEMBL29401064

SCHEMBL29401064

O=C(/C=C/c1ccc(O)cc1)Nc1ccccc1C(=O)O

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM2 O94759 3/20 0.81
LTB4R Q15722 1/20 0.81
TRPA1 O75762 7/20 0.79
TRPM8 Q7Z2W7 4/20 0.79
MEN1 O00255 3/20 0.73
KMT2A Q03164 3/20 0.73
NPC1 O15118 2/20 0.73
RAB9A P51151 2/20 0.73
SMN1; SMN2 Q16637 2/20 0.73
MAPT P10636 1/20 0.73
MMP1 P03956 8/20 0.73
MMP2 P08253 8/20 0.73
MMP9 P14780 8/20 0.73
PLA2G1B P04054 1/20 0.65
CYSLTR2 Q9NS75 1/20 0.65
CYSLTR1 Q9Y271 1/20 0.65
ALDH1A1 P00352 2/20 0.64
TP53 P04637 2/20 0.64
CYP3A4 P08684 2/20 0.64
HPGD P15428 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2778920 1.00 TRPM2 (0.81) TRPM2LTB4RTRPA1TRPM8MEN1
SCHEMBL2778922 1.00 TRPM2 (0.81) TRPM2LTB4RTRPA1TRPM8MEN1
SCHEMBL294402 0.92 TRPM2 (0.83) TRPM2LTB4RTRPA1TRPM8MEN1
SCHEMBL294403 0.92 TRPM2 (0.83) TRPM2LTB4RTRPA1TRPM8MEN1
SCHEMBL28809051 0.90 TRPM2 (1.00) TRPM2LTB4RTRPA1TRPM8MEN1
SCHEMBL28809046 0.90 TRPM2 (1.00) TRPM2LTB4RTRPA1TRPM8MEN1
SCHEMBL2780806 0.88 TRPA1 (1.00) TRPM2LTB4RTRPA1TRPM8MEN1
SCHEMBL2780699 0.88 TRPA1 (1.00) TRPM2LTB4RTRPA1TRPM8MEN1
SCHEMBL2780698 0.88 TRPA1 (1.00) TRPM2LTB4RTRPA1TRPM8MEN1
SCHEMBL2779997 0.88 TRPA1 (1.00) TRPM2LTB4RTRPA1TRPM8MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122005520-A Application of avenanthramide D in preparation of angiogenesis inhibiting drugs 桂林医科大学第一附属医院 2026-05-12 CN claimed
US-20230096303-A1 A Consumable Product Comprising Malted Cereals for Promoting Recovery at Physical Activity LANTMÄNNEN FUNCTIONAL FOODS AB (SE) 2023-03-30 US claimed
EP-4125984-A1 A CONSUMABLE PRODUCT COMPRISING MALTED CEREALS FOR PROMOTING RECOVERY AT PHYSICAL ACTIVITY Lantmännen Functional Foods AB (SE) 2023-02-08 EP claimed
CN-115605214-A Consumable product comprising malted cereals for promoting recovery of physical activity 兰特门内保健食品公司(SE) 2023-01-13 CN claimed
WO-2022128052-A1 MEDICAMENT FOR FIGHTING INFLAMMATORY CONDITIONS OF HUMAN SKIN SYMRISE AG (DE) 2022-06-23 WO claimed
EP-4103144-B1 COMPOSITIONS COMPRISING UV-FILTERS AND ONE OR MORE (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2026-05-27 EP disclosed
CN-122005520-A Application of avenanthramide D in preparation of angiogenesis inhibiting drugs 桂林医科大学第一附属医院 2026-05-12 CN disclosed
CN-122005520-A Application of avenanthramide D in preparation of angiogenesis inhibiting drugs 桂林医科大学第一附属医院 2026-05-12 CN disclosed
CN-122005520-A Application of avenanthramide D in preparation of angiogenesis inhibiting drugs 桂林医科大学第一附属医院 2026-05-12 CN disclosed
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2026-04-30 US disclosed
EP-4110277-B1 COMPOSITIONS COMPRISING (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2026-04-22 EP disclosed
EP-3045161-B1 Use of active mixtures of 1,2-hexanediol and 1,2-octanediol in cosmetic, pharmaceutical or dermatological emulsions SYMRISE AG (DE) 2026-03-25 EP disclosed
WO-2022122131-A1 COMPOSITIONS COMPRISING LIPOPHILIC COMPOUNDS AND ONE OR MORE (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2022-06-16 WO disclosed
WO-2022122135-A1 COMPOSITIONS COMPRISING (BIO)-ALKANEDIOLS WITH ANTIMICROBIALS FOR PRODUCT PROTECTION SYMRISE AG (DE) 2022-06-16 WO disclosed
US-20220175859-A1 Tetraselmis Extract SYMRISE AG (DE) 2022-06-09 US disclosed
US-11352587-B2 Fragrance mixtures SYMRISE AG (DE) 2022-06-07 US disclosed
WO-2022111829-A1 ESSENTIAL OILS OF CITRUS FRUITS FOR USE AS MEDICAMENT FOR INDUCED, INCREASED AND/OR ACCELERATED AUTOPHAGY IN HUMAN KERATINOCYTES SYMRISE AG (DE) 2022-06-02 WO disclosed
CN-109475120-B Antimicrobial compositions 西姆莱斯股份公司 2022-03-29 CN disclosed
CN-108366932-B Method for inhibiting or masking fishy smell 西姆莱斯股份公司 2022-03-15 CN disclosed
US-20220054378-A1 COMPOSITIONS COMPRISING ODORLESS 1,2-PENTANEDIOL SYMRISE AG (DE) 2022-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11352587-B2 Fragrance mixtures DHCR24, FAM120A, TRPA1 TRPM2 211/4885LTB4R 443/4885TRPA1 3/4885
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME PIGS, TAS2R13, CEL TRPM2 4334/4885LTB4R 4657/4885TRPA1 3165/4885
US-20220175859-A1 Tetraselmis Extract DPM1, CD63, PTPMT1 TRPM2 275/4885LTB4R 3231/4885TRPA1 656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.