Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | F2 | P00734 | 2/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | PKLR | P30613 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8813894 | 0.93 | LMNA (0.57) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| SCHEMBL1952494 | 0.83 | LMNA (0.68) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| SCHEMBL8813715 | 0.83 | ALDH1A1 (0.52) | LMNAL3MBTL1TSHR | |
| SCHEMBL2064679 | 0.81 | L3MBTL1 (0.59) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| SCHEMBL193715 | 0.79 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| SCHEMBL12234418 | 0.79 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| SCHEMBL1588805 | 0.79 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| SCHEMBL193716 | 0.79 | LMNA (1.00) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| SCHEMBL2238091 | 0.79 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 | |
| SCHEMBL6113091 | 0.79 | LMNA (0.63) | LMNAL3MBTL1F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 936 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847568-B1 | THERMOSETTING RESIN COMPOSITION, THERMOSETTING-RESIN MOLDING MATERIAL, AND CURED OBJECT OBTAINED THEREFROM | SUMITOMO BAKELITE CO (JP) | 2015-05-20 | — | — | EP | claimed |
| US-6197972-B1 | CHEMICAL INTERMEDIATES FOR ANTICHOLESTEROL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-03-06 | — | — | US | claimed |
| US-5977112-A | Process of making substituted benzofurans | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-11-02 | — | — | US | claimed |
| US-5753652-A | Antiretroviral hydrazine derivatives | NOVARTIS CORPORATION (US) | 1998-05-19 | — | — | US | claimed |
| EP-0521827-B1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA GEIGY AG (CH) | 1996-09-25 | — | — | EP | claimed |
| EP-0447171-B1 | Polysulfate of cyclodextrin derivative and process for preparing the same | TANABE SEIYAKU CO (JP) | 1994-11-02 | — | — | EP | claimed |
| US-5248675-A | Viricides for HIV | TANABE SEIYAKU CO., LTD. | 1993-09-28 | — | — | US | claimed |
| EP-0447171-A2 | Polysulfate of cyclodextrin derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1991-09-18 | — | — | EP | claimed |
| US-20240238257-A1 | SYNTHETIC METHODS FOR PREPARATION OF 4-(2-CHLORO-4-METHOXY-5-METHYLPHENYL)-N-[(1S)-2-CYCLOPROPYL-1-(3-FLUORO-4-METHYLPHENYL)ETHYL]-5-METHYL-N-PROP-2-YNYL-1,3-THIAZOL-2-AMINE | SANOFI (FR) | 2024-07-18 | — | — | US | disclosed |
| EP-4400492-A1 | ACRIDINE COMPOUND | OSAKA UNIVERSITY (JP) | 2024-07-17 | — | — | EP | disclosed |
| US-20240208999-A1 | HETEROCYCLIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-06-27 | — | — | US | disclosed |
| CN-118103359-A | Preparation method of eribulin derivative | 江苏恒瑞医药股份有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112239407-B | Diester compound having dimethylcyclobutane ring, method for producing the same, and method for producing dimethylcyclobutane compound derived from the same | 信越化学工业株式会社 | 2024-05-28 | — | — | CN | disclosed |
| EP-4370507-A1 | HYDROGENATED QUINOXALINES | Otsuka Pharmaceutical Co., Ltd. (JP) | 2024-05-22 | — | — | EP | disclosed |
| US-3966703-A | Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |
| US-3956334-A | CHOLESTEROL AND TRIGLYCERIDE LOWERING ACTIVITY IN BLOOD | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-05-11 | — | — | US | disclosed |
| US-3951986-A | Novel 2-propanol derivatives and preparation thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-20 | — | — | US | disclosed |
| US-3948949-A | ANTIPHOLISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER (DT) | 1976-04-06 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |
| US-3932487-A | HYPOTENSIVE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238257-A1 | SYNTHETIC METHODS FOR PREPARATION OF 4-(2-CHLORO-4-METHOXY-5-METHYLPHENYL)-N-[(1S)-2-CYCLOPROPYL-1-(3-FLUORO-4-METHYLPHENYL)ETHYL]-5-METHYL-N-PROP-2-YNYL-1,3-THIAZOL-2-AMINE | CYP21A2, NR5A1, HSD3B1 | LMNA 2463/4885L3MBTL1 4402/4885F2 3286/4885 |
| US-20240208999-A1 | HETEROCYCLIC COMPOUND | AHR, PDGFRA, PDGFRB | LMNA 3284/4885L3MBTL1 4662/4885F2 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.