SCHEMBL29402789

SCHEMBL29402789

CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCCN=C(N)N)[C@@H](C)O)C(N)=O

nearest known ligand 0.63

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ OPRK1 P41145 2/20 0.63
▸ OPRM1 P35372 2/20 0.63
▸ OPRD1 P41143 2/20 0.63
▸ IL23R Q5VWK5 3/20 0.57
▸ KISS1R Q969F8 4/20 0.56
▸ NPY1R P25929 1/20 0.55
▸ NPY2R P49146 1/20 0.55
▸ NPY4R P50391 1/20 0.55
▸ NPBWR1 P48145 2/20 0.54
▸ CRHR1 P34998 1/20 0.53
▸ CRHR2 Q13324 1/20 0.53
▸ NTSR1 P30989 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29854419 0.89 CRHR1 (0.64) IL23RCRHR1CRHR2
SCHEMBL29582948 0.86 CRHR1 (0.68) CRHR1CRHR2
SCHEMBL29732401 0.85 TFPI (0.62) NPBWR1CRHR1CRHR2
SCHEMBL29468905 0.84 CRHR1 (0.57) CRHR1CRHR2
SCHEMBL30589713 0.83 CRHR1 (0.59) IL23RKISS1RCRHR1CRHR2
SCHEMBL31332318 0.83 QRFPR (0.57) OPRK1OPRM1OPRD1NPBWR1
SCHEMBL31332222 0.83 OPRK1 (0.71) OPRK1OPRM1OPRD1KISS1RNPY1R
SCHEMBL11309694 0.83 OPRM1 (0.52) OPRK1OPRM1OPRD1IL23R
SCHEMBL11309707 0.83 OPRM1 (0.52) OPRK1OPRM1OPRD1IL23R
SCHEMBL29517084 0.82 OPRK1 (0.59) OPRK1OPRD1IL23RNPBWR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230145599-A1 Microneedle Array Delivery of Adenovirus Vectored Vaccines With and Without Adjuvants UNIV OF PITTSBURGH OF THE COMMONWELTH SYSTEM OF HIGHER EDUCATION (US) 2023-05-11 — — US claimed
EP-4132466-A1 MICRONEEDLE ARRAY DELIVERY OF ADENOVIRUS VECTORED VACCINES WITH AND WITHOUT ADJUVANTS University of Pittsburgh - of the Commonwealth System of Higher Education (US) 2023-02-15 — — EP claimed
EP-4114462-A1 2019-NCOV SUBUNIT VACCINE AND MICRONEEDLE ARRAY DELIVERY SYSTEM University of Pittsburgh - of the Commonwealth System of Higher Education (US) 2023-01-11 — — EP claimed
WO-2022038131-A1 METHOD FOR THE PREDICTION OF PROGRESSION OR PROGNOSIS OF THE RESPONSE OF A SUBJECT SUFFERING FROM ACUTE ORGAN DAMAGE Plus Vitech, S.L. (ES) 2022-02-24 — — WO claimed
US-20260049331-A1 Sense-and-Response of Proteins, Peptides, and Small Molecules Using Ligand-Induced Dimerization Activating RNA Editing (LIDAR) UNIV LELAND STANFORD JUNIOR (US) 2026-02-19 — — US disclosed
EP-4674959-A1 NICKING ENZYME, DNA EDITING SYSTEM, TARGET DNA EDITING METHOD, AND METHOD FOR PRODUCING CELL IN WHICH TARGET DNA IS EDITED Sumitomo Chemical Company, Limited (JP) 2026-01-07 — — EP disclosed
US-20250270330-A1 TREATMENT OF HEADACHE DISORDERS WITH NK3 MODULATORS KALLYOPE, INC. 2025-08-28 — — US disclosed
US-20250223580-A1 PROGRAMMABLE NUCLEASE-PEPTIDASE COMPOSITIONS THE BROAD INSTITUTE, INC. 2025-07-10 — — US disclosed
WO-2025137264-A1 SMALL MOLECULE SURROGATE FOR A NEUTRALIZATION EPITOPE ON THE ZIKA VIRUS ENVELOPE PROTEIN UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2025-06-26 — — WO disclosed
US-20250179130-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS ON TARGET THERAPEUTICS LLC 2025-06-05 — — US disclosed
CN-114867819-B Carbon quantum dot and use thereof 北京碳纳医疗科技有限公司 2025-03-28 — — CN disclosed
EP-3100729-B1 USE OF NON-PEPTIDE NK1 ANTAGONISTS IN A PREDETERMINED DOSE FOR THE TREATMENT OF CANCER SERVICIO ANDALUZ DE SALUD (ES) 2025-03-19 — — EP disclosed
WO-2022170509-A1 TCR AND APPLICATION THEREOF 深圳普瑞金生物药业有限公司 2022-08-18 — — WO disclosed
CN-114867819-A Carbon quantum dots and uses thereof 北京碳纳医疗科技有限公司 2022-08-05 — — CN disclosed
CN-114599382-A Agonists of Tacr2 哥本哈根大学 2022-06-07 — — CN disclosed
EP-3997104-A1 COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF 3B Pharmaceuticals GmbH (DE) 2022-05-18 — — EP disclosed
WO-2021087645-A9 USE OF CARBON QUANTUM DOTS FOR DETECTING OR TREATING CNS CANCER OR TUMOR BEIJING NORMAL UNIVERSITY (CN) 2022-05-12 — — WO disclosed
US-20220135633-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS ON TARGET THERAPEUTICS LLC 2022-05-05 — — US disclosed
US-20220087930-A1 SARS-CoV-2 Subunit Vaccine and Microneedle Array Delivery System UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2022-03-24 — — US disclosed
WO-2022038131-A1 METHOD FOR THE PREDICTION OF PROGRESSION OR PROGNOSIS OF THE RESPONSE OF A SUBJECT SUFFERING FROM ACUTE ORGAN DAMAGE Plus Vitech, S.L. (ES) 2022-02-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220135633-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS LDLR, HDLBP, LIPG OPRK1 2530/4885OPRM1 1737/4885OPRD1 2716/4885
US-20260049331-A1 Sense-and-Response of Proteins, Peptides, and Small Molecules Using Ligand-Induced Dimerization Activating RNA Editing (LIDAR) ADAR, ZFR, SLIRP OPRK1 2852/4885OPRM1 1894/4885OPRD1 2320/4885
US-20250179130-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS LDLR, HDLBP, LIPG OPRK1 2530/4885OPRM1 1737/4885OPRD1 2716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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