Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL191092 | 0.84 | CHAT (0.45) | NFE2L2MAOBALDH1A1MEN1LMNA | |
| SCHEMBL191091 | 0.84 | CHAT (0.45) | NFE2L2MAOBALDH1A1MEN1LMNA | |
| SCHEMBL339221 | 0.81 | — | — | |
| SCHEMBL5664436 | 0.81 | — | — | |
| SCHEMBL28245646 | 0.81 | NFE2L2 (0.57) | NFE2L2ACHEPTGS1 | |
| SCHEMBL2938818 | 0.81 | FGF23 (0.46) | NFE2L2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL20580084 | 0.77 | NFE2L2 (0.47) | NFE2L2MAOBMEN1KMT2AMAOA | |
| SCHEMBL7131085 | 0.77 | AHR (0.50) | NFE2L2AHRMAOBALDH1A1KDM4E | |
| SCHEMBL2931689 | 0.77 | TRPA1 (0.61) | NFE2L2AHRNPC1RAB9AALDH1A1 | |
| SCHEMBL28242387 | 0.77 | AHR (0.46) | NFE2L2AHRMAOBALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1978967-B1 | QUINAZOLINONE DERIVATIVES AS VANILLOID ANTAGONISTS | NOVARTIS AG (CH) | 2010-09-22 | — | — | EP | claimed |
| CN-111647018-B | Preparation method of phosphorus center chiral compound | 杭州师范大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-111647018-A | Preparation method of phosphorus center chiral compound | 杭州师范大学 | 2020-09-11 | — | — | CN | disclosed |
| CN-108558927-B | Silicon stereocenter chiral compound and synthesis method thereof | 杭州师范大学 | 2020-06-19 | — | — | CN | disclosed |
| EP-1978967-B1 | QUINAZOLINONE DERIVATIVES AS VANILLOID ANTAGONISTS | NOVARTIS AG (CH) | 2010-09-22 | — | — | EP | disclosed |