Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28714141 | 0.93 | HDAC3 (0.50) | ALOX15HTTHDAC3ALDH1A1PLK1 | |
| SCHEMBL29404844 | 0.89 | RAB9A (0.49) | ALOX15HTTALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL28714142 | 0.86 | HDAC3 (0.47) | ALOX15HTTHDAC3ALDH1A1PLK1 | |
| SCHEMBL27255825 | 0.85 | ALOX15 (0.51) | ALOX15HTTHDAC3ALDH1A1PLK1 | |
| SCHEMBL23930129 | 0.84 | ALDH1A1 (0.61) | ALOX15HTTHDAC3ALDH1A1PLK1 | |
| SCHEMBL23930005 | 0.82 | HDAC3 (0.50) | ALOX15HTTHDAC3ALDH1A1PLK1 | |
| SCHEMBL28702029 | 0.81 | TP53 (0.54) | HTTALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29404861 | 0.80 | TACR1 (0.48) | POLBMEN1KMT2A | |
| SCHEMBL3136961 | 0.79 | ALDH1A1 (0.53) | ALOX15HTTHDAC3ALDH1A1NPC1 | |
| SCHEMBL359850 | 0.79 | ALOX15 (0.58) | ALOX15HTTHDAC3ALDH1A1PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181122-A | Benzyl thioether compound and preparation method thereof | 苏州照固新材料科技有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-114181122-A | Benzyl thioether compound and preparation method thereof | 苏州照固新材料科技有限公司 | 2022-03-15 | — | — | CN | disclosed |