SCHEMBL29404861

SCHEMBL29404861

COC(=O)C(=O)OCc1ccc2ccccc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 1/20 0.48
CYP1A2 P05177 2/20 0.47
PPARG P37231 3/20 0.47
PPARD Q03181 2/20 0.47
PPARA Q07869 2/20 0.47
POLB P06746 1/20 0.47
NCOA2 Q15596 1/20 0.47
NCOA1 Q15788 1/20 0.47
CTDSP1 Q9GZU7 1/20 0.47
NCOA3 Q9Y6Q9 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
SLC1A3 P43003 1/20 0.47
SLC1A2 P43004 1/20 0.47
SLC1A1 P43005 1/20 0.47
CYP2A6 P11509 1/20 0.46
CTSL P07711 1/20 0.44
CTSB P07858 1/20 0.44
CTSS P25774 1/20 0.44
ALOX5 P09917 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28936084 0.92 CYP1A2 (0.54) TACR1CYP1A2SLC1A3SLC1A2SLC1A1
SCHEMBL20182728 0.85 TACR1 (0.55) TACR1CYP1A2PPARGPPARDPPARA
SCHEMBL28936085 0.83 CYP1A2 (0.54) TACR1CYP1A2MEN1KMT2ASLC1A3
SCHEMBL29503697 0.83 TACR1 (0.47) TACR1CYP1A2SLC1A3SLC1A2SLC1A1
SCHEMBL2619047 0.83 TACR1 (0.47) TACR1CYP1A2SLC1A3SLC1A2SLC1A1
SCHEMBL6910495 0.81 SLC1A3 (0.50) TACR1CYP1A2SLC1A3SLC1A2SLC1A1
SCHEMBL487508 0.81 ALDH1A1 (0.61) TACR1CYP1A2SLC1A3SLC1A2SLC1A1
SCHEMBL12057416 0.81 TOP2A (0.54) TACR1CYP1A2SLC1A3SLC1A2SLC1A1
SCHEMBL29404968 0.80 ALOX15 (0.55) POLBMEN1KMT2A
SCHEMBL29404844 0.80 RAB9A (0.49) PPARGMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114181122-A Benzyl thioether compound and preparation method thereof 苏州照固新材料科技有限公司 2022-03-15 CN claimed
CN-114181122-A Benzyl thioether compound and preparation method thereof 苏州照固新材料科技有限公司 2022-03-15 CN disclosed