Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16119858 | 0.84 | ALDH1A1 (0.43) | ADORA2AADORA1ALDH1A1PTGS1PTGS2 | |
| SCHEMBL14290476 | 0.77 | TDO2 (0.46) | TDO2DHFRADORA2AADORA1NPC1 | |
| SCHEMBL2317547 | 0.77 | ALDH1A1 (0.43) | ADORA2AADORA1ALDH1A1PTGS1PTGS2 | |
| SCHEMBL21770966 | 0.75 | ALDH1A1 (0.52) | TDO2DHFRADORA2AADORA1MAOB | |
| SCHEMBL25593133 | 0.73 | TDO2 (0.43) | TDO2DHFRADORA2AADORA1MAOB | |
| SCHEMBL6011269 | 0.73 | ALDH1A1 (0.54) | TDO2DHFRADORA2AADORA1MAOB | |
| SCHEMBL6571989 | 0.73 | ALDH1A1 (0.54) | TDO2DHFRADORA2AADORA1MAOB | |
| SCHEMBL3835519 | 0.72 | PTPRC (0.47) | TDO2DHFRADORA2AADORA1MAOB | |
| SCHEMBL29575632 | 0.72 | ALDH1A1 (0.58) | TDO2DHFRADORA2AADORA1MAOB | |
| SCHEMBL398850 | 0.72 | ALDH1A1 (0.58) | TDO2DHFRADORA2AADORA1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7750186-B2 | Methods for the manufacture of biphenyl amines | BAYER CROPSCIENCE AG (DE) | 2010-07-06 | — | — | US | disclosed |
| US-20080194835-A1 | Methods for the Manufacture of Biphenyl Amines | BAYER GROPSCIENCE AG (DE) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194835-A1 | Methods for the Manufacture of Biphenyl Amines | DDT, AADAC, CYP1B1 | TDO2 189/4885DHFR 183/4885ADORA2A 1110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.