Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDO2 | P48775 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29575632 | 1.00 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TDO2ADORA2AADORA1 | |
| SCHEMBL21933948 | 0.92 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TDO2ADORA2AADORA1 | |
| SCHEMBL9862849 | 0.84 | NPC1 (0.50) | ALDH1A1TDO2ADORA2AADORA1DHFR | |
| SCHEMBL5162068 | 0.84 | ALDH1A1 (0.71) | ALDH1A1HSD17B10ADORA2ADHFRNPC1 | |
| SCHEMBL399109 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HSD17B10ADORA2AADORA1DHFR | |
| SCHEMBL28623583 | 0.82 | TDO2 (0.47) | ALDH1A1TDO2ADORA2AADORA1DHFR | |
| SCHEMBL17010271 | 0.81 | DHFR (0.49) | ALDH1A1TDO2ADORA2AADORA1DHFR | |
| SCHEMBL5050877 | 0.80 | CYP2A6 (0.52) | TDO2ADORA2AADORA1DHFRNPC1 | |
| SCHEMBL6571989 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HSD17B10TDO2ADORA2AADORA1 | |
| SCHEMBL6011269 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TDO2ADORA2AADORA1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252140-B1 | PYRROLECARBOXAMIDES AND PYRROLETHIOAMIDES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-05-13 | — | — | EP | claimed |
| US-20090011935-A1 | Method of Inducing Tolerance of Plants Against Bacterioses | BASF SE (DE) | 2009-01-08 | — | — | US | claimed |
| EP-1996018-A2 | METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES | BASF SE (DE) | 2008-12-03 | — | — | EP | claimed |
| WO-2007104658-A2 | METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES | BASF SE (DE) | 2007-09-20 | — | — | WO | claimed |
| CN-114573546-B | Organic compound and organic electroluminescent element comprising same | 材料科学有限公司 | 2024-02-23 | — | — | CN | disclosed |
| US-20230010535-A1 | ELECTROACTIVE COMPOUNDS | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2023-01-12 | — | — | US | disclosed |
| US-20230010535-A1 | ELECTROACTIVE COMPOUNDS | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2023-01-12 | — | — | US | disclosed |
| CN-114573546-A | Organic compound and organic electroluminescent element comprising same | 材料科学有限公司 | 2022-06-03 | — | — | CN | disclosed |
| WO-2021126593-A1 | ELECTROACTIVE COMPOUNDS | DUPONT ELECTRONICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |
| EP-3705477-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | Vertex Pharmaceuticals Incorporated (US) | 2020-09-09 | — | — | EP | disclosed |
| US-10662192-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2020-05-26 | — | — | US | disclosed |
| EP-3216787-B1 | INTERMEDIATES FOR THE PREPARATION OF MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMA (US) | 2020-02-19 | — | — | EP | disclosed |
| EP-1856024-A1 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF AKTIENGESELLSCHAFT (DE) | 2007-11-21 | — | — | EP | disclosed |
| WO-2007104658-A2 | METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES | BASF SE (DE) | 2007-09-20 | — | — | WO | disclosed |
| WO-2007003603-A2 | FUNGICIDE MIXTURES BASED ON 3-MONOSUBSTITUTED PYRAZOLE CARBOXYLIC ACID BIPHENYL AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2007-01-11 | — | — | WO | disclosed |
| WO-2006092429-A1 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF AKTIENGESELLSCAHFT (DE) | 2006-09-08 | — | — | WO | disclosed |
| US-20060074075-A1 | including cystic fibrosis transmembrane conductance regulator (\"CFTR\"), used for treating genetic disorders; respiratory system disorders | VERTEX PHARMACEUTICALS INCORPORATED | 2006-04-06 | — | — | US | disclosed |
| WO-2000075135-A1 | BIARYL INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2000-12-14 | — | — | WO | disclosed |
| EP-1023277-A1 | NOVEL 3,4-DIARYLTHIAZOLIN-2-ONE OR -2-THIONE DERIVATIVES, PREPARATION METHODS AND USES IN THERAPY | LABORATOIRES UPSA (FR) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999018093-A1 | NOVEL 3,4-DIARYLTHIAZOLIN-2-ONE OR -2-THIONE DERIVATIVES, PREPARATION METHODS AND USES IN THERAPY | LABORATOIRES UPSA (FR) | 1999-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090011935-A1 | Method of Inducing Tolerance of Plants Against Bacterioses | BROX, CAT, SLC11A2 | ALDH1A1 2207/4885HSD17B10 2379/4885TDO2 493/4885 |
| US-20230010535-A1 | ELECTROACTIVE COMPOUNDS | NR4A2, NR2C2, ESR2 | ALDH1A1 3088/4885HSD17B10 1152/4885TDO2 3202/4885 |
| US-10662192-B2 | Modulators of ATP-binding cassette transporters | CFTR, ABCB1, ABCC2 | ALDH1A1 2165/4885HSD17B10 1468/4885TDO2 4560/4885 |
| US-20060074075-A1 | including cystic fibrosis transmembrane conductance regulator (\"CFTR\"), used for treating genetic disorders; respiratory system disorders | CFTR, ABCC4, ABCC2 | ALDH1A1 2221/4885HSD17B10 1602/4885TDO2 4575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.