Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | FADS1 | O60427 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14685847 | 0.83 | GABRP (0.45) | TDO2DHFRMAPK14GABRPGABRD | |
| SCHEMBL3783916 | 0.81 | MAOA (0.47) | ALDH1A1TAAR1MAP4K4CHRM3NPY5R | |
| SCHEMBL6571989 | 0.81 | ALDH1A1 (0.54) | TDO2DHFRPGRADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL6572248 | 0.80 | ALDH1A1 (0.52) | TDO2DHFRPGRADORA2AADORA1 | |
| SCHEMBL3950704 | 0.79 | ALDH1A1 (0.45) | TDO2MAPK14NPC1RAB9AALDH1A1 | |
| SCHEMBL29492484 | 0.79 | ALDH1A1 (0.54) | ADORA2AADORA1ALDH1A1TAAR1 | |
| SCHEMBL3793169 | 0.79 | ALDH1A1 (0.54) | ADORA2AADORA1ALDH1A1TAAR1 | |
| SCHEMBL10094663 | 0.79 | ESR2 (0.46) | TDO2MAPK14GABRPGABRDGABRA1 | |
| SCHEMBL3388331 | 0.79 | PTGS2 (0.46) | ADORA2AADORA1ALDH1A1CHRM1CHRM2 | |
| SCHEMBL5123382 | 0.78 | CNR1 (0.55) | TDO2DHFRMAPK14GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008014905-A2 | 3-DIFLUOROMETHYLPYRAZOLYLCARBOXANILIDES | BAYER CROPSCIENCE AG (DE) | 2008-02-07 | — | — | WO | disclosed |