SCHEMBL29409552

SCHEMBL29409552

FC(F)(F)Nc1ccc(-c2ccc(NC(F)(F)F)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 18/20 0.44
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HDAC1 Q13547 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7003928 0.90 KIF11 (0.50) KIF11HTTSMN1; SMN2HDAC1HDAC7
SCHEMBL8068086 0.88 KIF11 (0.52) KIF11HTTSMN1; SMN2L3MBTL1
SCHEMBL3786178 0.80 MAPT (0.44) HTTSMN1; SMN2
SCHEMBL3651020 0.78 POLB (0.44) HDAC1HDAC7HDAC8HDAC6
SCHEMBL2722652 0.78 MAPT (0.50) HTTHDAC1HDAC7HDAC8
SCHEMBL6313165 0.78 MAPT (0.42) KIF11HTTSMN1; SMN2L3MBTL1
SCHEMBL28444452 0.78 MAPT (0.42) KIF11L3MBTL1
SCHEMBL412378 0.77 ALDH1A1 (0.45) SMN1; SMN2L3MBTL1
SCHEMBL22872345 0.75 SNCA (0.49) HDAC1HDAC6
Fluoride SCHEMBL5178837 0.74 ALDH1A1 (0.43) SMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115340764-A Polyamideimide film and image display device including the same SK新技术株式会社 2022-11-15 CN claimed
CN-114466900-B Polyimide base film and window covering film using same SK新技术株式会社 2024-02-23 CN disclosed
CN-116917377-A Optically transparent polyamideimide 齐默尔根公司 2023-10-20 CN disclosed
CN-115340764-A Polyamideimide film and image display device including the same SK新技术株式会社 2022-11-15 CN disclosed
CN-114364718-A Polyamide-imide polymer and method for producing same 索尔维特殊聚合物美国有限责任公司 2022-04-15 CN disclosed
CN-114175859-A Insulating layer for multilayer printed circuit board, multilayer printed circuit board including the same, and method for manufacturing the same 株式会社LG化学 2022-03-11 CN disclosed